Systems biology in psychiatric research : from high-throughput data to mathematical modeling /
Systems biology in psychiatric research : from high-throughput data to mathematical modeling /
edited by Felix Tretter [and others].
- Weinheim : Wiley-VCH, ©2010.
- 1 online resource (xx, 358 pages) : illustrations
Includes bibliographical references and index.
Front Matter -- Introduction. Part Introduction -- Philosophical Aspects of Neuropsychiatry / Felix Tretter -- Neuropsychiatry : Subject, Concepts, Methods, and Computational Models / Felix Tretter, Peter J Gebicke-Haerter -- Introduction to Systems Biology / Marvin Schulz, Edda Klipp -- Mind over Molecule: Systems Biology for Neuroscience and Psychiatry / Denis Noble -- Basics. Part Introduction -- Neuropsychiatry, Psychopathology, and Nosology : Symptoms, Syndromes, and Endophenotypes / Wolfram Kawohl, Paul Hoff -- System Properties of Populations of Neurons in Cerebral Cortex / Walter J Freeman -- Dopamine and the Electrophysiology of Prefrontal Cortical Networks / Patricio O'Donnell -- Research in Molecular Psychiatry. Part Introduction -- Nicotinic Cholinergic Signaling in the Human Brain : Systems Perspective / Arian Mobascher, Georg Winterer -- Progress in Psychopharmacotherapy though Molecular Imaging / Ingo Vernaleken, Gerhard Gruender, Paul Cumming -- The Marriage of Phenomics and Genetical Genomics: A Systems Approach to Complex Trait Analysis / Laura M Saba, Paula L Hoffman, Lawrence E Hunter, Boris Tabakoff -- Data Mining and Modeling. Part Introduction -- From Communicational to Computational: Systems Modeling Approaches for Psychiatric Research / Eduardo R Mendoza -- Network Dynamics as an Interface between Modeling and Experiment in Systems Biology / James Smith, Marc-Thorsten Hutt -- Some Useful Mathematical Tools to Transform Microarray Data into Interactive Molecular Networks / Franziska Matthaus, V Anne Smith, Peter J Gebicke-Haerter -- Biochemical Networks in Psychiatric Disease / Maria Lindskog, Geir Halnes, Rodrigo F Oliveira, Jeanette Hellgren Kotaleski, Kim T Blackwell -- Local Cortical Dynamics Related to Mental Illnesses / Marco Loh, Edmund T Rolls, Gustavo Deco -- Epilogue / Peter J Gebicke-Haerter -- Index.
This first book to provide a comprehensive overview of the recent progress made in this break-through approach includes expert contributions from a variety of disciplines. Particular focus is placed on high-throughput methods and the analysis of data thus obtained, as well as their use in silico experiments so as to gain an insight into the complex biological processes in neuronal systems. A must-have for everyone working in psychiatric research.
9783527630271 3527630279 9783527630288 3527630287 1282690647 9781282690646 3527325034 9783527325030
10.1002/9783527630271 doi 9786612690648
10.1002/9783527630271 Wiley InterScience http://www3.interscience.wiley.com
Psychiatry--Research--Methodology.
Bioinformatics.
Psychiatry.
Biomedical Research--methods.
Systems Biology.
MEDICAL--Psychiatry--General.
PSYCHOLOGY--Psychopathology--General.
PSYCHOLOGY--Clinical Psychology.
PSYCHOLOGY--Mental Illness.
MEDICAL--Mental Health.
Bioinformatics.
Psychiatry--Research--Methodology.
Electronic books.
RC337 / .S97 2010
616.890072
WM 20
Includes bibliographical references and index.
Front Matter -- Introduction. Part Introduction -- Philosophical Aspects of Neuropsychiatry / Felix Tretter -- Neuropsychiatry : Subject, Concepts, Methods, and Computational Models / Felix Tretter, Peter J Gebicke-Haerter -- Introduction to Systems Biology / Marvin Schulz, Edda Klipp -- Mind over Molecule: Systems Biology for Neuroscience and Psychiatry / Denis Noble -- Basics. Part Introduction -- Neuropsychiatry, Psychopathology, and Nosology : Symptoms, Syndromes, and Endophenotypes / Wolfram Kawohl, Paul Hoff -- System Properties of Populations of Neurons in Cerebral Cortex / Walter J Freeman -- Dopamine and the Electrophysiology of Prefrontal Cortical Networks / Patricio O'Donnell -- Research in Molecular Psychiatry. Part Introduction -- Nicotinic Cholinergic Signaling in the Human Brain : Systems Perspective / Arian Mobascher, Georg Winterer -- Progress in Psychopharmacotherapy though Molecular Imaging / Ingo Vernaleken, Gerhard Gruender, Paul Cumming -- The Marriage of Phenomics and Genetical Genomics: A Systems Approach to Complex Trait Analysis / Laura M Saba, Paula L Hoffman, Lawrence E Hunter, Boris Tabakoff -- Data Mining and Modeling. Part Introduction -- From Communicational to Computational: Systems Modeling Approaches for Psychiatric Research / Eduardo R Mendoza -- Network Dynamics as an Interface between Modeling and Experiment in Systems Biology / James Smith, Marc-Thorsten Hutt -- Some Useful Mathematical Tools to Transform Microarray Data into Interactive Molecular Networks / Franziska Matthaus, V Anne Smith, Peter J Gebicke-Haerter -- Biochemical Networks in Psychiatric Disease / Maria Lindskog, Geir Halnes, Rodrigo F Oliveira, Jeanette Hellgren Kotaleski, Kim T Blackwell -- Local Cortical Dynamics Related to Mental Illnesses / Marco Loh, Edmund T Rolls, Gustavo Deco -- Epilogue / Peter J Gebicke-Haerter -- Index.
This first book to provide a comprehensive overview of the recent progress made in this break-through approach includes expert contributions from a variety of disciplines. Particular focus is placed on high-throughput methods and the analysis of data thus obtained, as well as their use in silico experiments so as to gain an insight into the complex biological processes in neuronal systems. A must-have for everyone working in psychiatric research.
9783527630271 3527630279 9783527630288 3527630287 1282690647 9781282690646 3527325034 9783527325030
10.1002/9783527630271 doi 9786612690648
10.1002/9783527630271 Wiley InterScience http://www3.interscience.wiley.com
Psychiatry--Research--Methodology.
Bioinformatics.
Psychiatry.
Biomedical Research--methods.
Systems Biology.
MEDICAL--Psychiatry--General.
PSYCHOLOGY--Psychopathology--General.
PSYCHOLOGY--Clinical Psychology.
PSYCHOLOGY--Mental Illness.
MEDICAL--Mental Health.
Bioinformatics.
Psychiatry--Research--Methodology.
Electronic books.
RC337 / .S97 2010
616.890072
WM 20