Drug disposition and pharmacokinetics : from principles to applications /
Curry, Stephen H.
Drug disposition and pharmacokinetics : from principles to applications / Stephen H. Curry and Robin Whelpton - Chichester, West Sussex : Wiley-Blackwell, 2010 - 365 p. : ill. ; 27 cm.
Includes bibliographical references and index
Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology
9780470684467 (cloth) RM233.60
Pharmacokinetics
Biopharmaceutics
Pharmaceutical Preparations--metabolism
QV38 / .C976d 2011 9
Drug disposition and pharmacokinetics : from principles to applications / Stephen H. Curry and Robin Whelpton - Chichester, West Sussex : Wiley-Blackwell, 2010 - 365 p. : ill. ; 27 cm.
Includes bibliographical references and index
Chemical introduction : sources, classification, and chemical properties of drugs -- Drug administration and distribution -- Drug elimination -- Elementary pharmacokinetics -- More complex and model independent pharmacokinetic models -- Kinetics of metabolism and excretion -- Further consideration of clearance, and physiological modelling -- Drug formulation : bioavailability, bioequivalence and controlled-release preparations -- Factors affecting plasma concentrations -- Pharmacogenetics and pharmacogenomics -- Developmental pharmacology and age-related phenomena -- Effects of disease on drug disposition -- Quantitative pharmacological relationships -- Simultaneous measurement of concentrations and effect, and pharmacokinetic/pharmacodynamic (PK/PD) modelling -- Drug monitoring in therapeutics -- Drug interactions -- Drug metabolism and pharmacokinetics in toxicology
9780470684467 (cloth) RM233.60
Pharmacokinetics
Biopharmaceutics
Pharmaceutical Preparations--metabolism
QV38 / .C976d 2011 9