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006			m o d
007			cr |||||||||||
008			171212s2016 nju ob 001 0 eng
010			_a2015-047720
020			_a9781118822357 (pdf)
020			_a1118822358 (pdf)
020			_a9781118822364 (epub)
020			_a1118822366 (epub)
020			_z9781118822296 (hardback)
020			_a9781118828083
020			_a1118828089
020			_a1118822293 (hardback)
020			_a9781118822296 (hardback)
035			_a(OCoLC)931227028 _z(OCoLC)950465980
035			_a(OCoLC)ocn931227028
039		9	_a201902121536 _bros _y12-12-2017 _zhafiz _wMYUKM (1).mrc _x737
040			_aDLC _beng _erda _cDLC _dOCLCF _dNST _dDG1 _dYDXCP _dIDEBK _dOCLCO _dRECBK _dEBLCP _dCOO _dDG1
042			_apcc
049			_aMAIN
050	0	0	_aTP248.65.E59
066			_c(S
072		7	_aSCI _x013060 _2bisacsh
072		7	_aTEC _x009010 _2bisacsh
082	0	0	_a660 _223
245	0	0	_aGreen biocatalysis / _cedited by Ramesh N. Patel.
264		1	_aHoboken, NJ : _bJohn Wiley & Sons, _c2016.
300			_a1 online resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bn _2rdamedia
338			_aonline resource _bnc _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0		_6880-01 _aTitle Page; Copyright Page; Contents; Preface; About the Editor; Contributors ; Chapter 1 Biocatalysis and Green Chemistry ; 1.1 INTRODUCTION TO SUSTAINABLE DEVELOPMENT AND GREEN CHEMISTRY; 1.2 GREEN CHEMISTRY METRICS; 1.3 ENVIRONMENTAL IMPACT AND SUSTAINABILITY METRICS; 1.4 SOLVENTS; 1.5 THE ROLE OF CATALYSIS; 1.6 BIOCATALYSIS AND GREEN CHEMISTRY; 1.7 EXAMPLES OF GREEN BIOCATALYTIC PROCESSES; 1.7.1 A Chemoenzymatic Process for Pregabalin; 1.7.2 A Three-Enzyme Process for Atorvastatin Intermediate ; 1.7.3 Enzymatic Synthesis of Sitagliptin.
520			_a'This book describes the enzyme-driven syntheses of industrially important compounds and chiral intermediates for chemicals and pharmaceuticals. The chapters describe recent technological advances in enzymatic and microbial transformations and are written by internationally renowned scientists and professors. The synthesis of industrially important molecules is described from the starting substrate to the final product and includes detailed mechanisms. This book addresses the use of various types of reactions catalyzed by microbial cells or enzymes derived from microbes in the production of industrially useful compounds and a variety of drugs. The production of chiral alcohols, amines, unnatural amino acids, esters, carboxylic acids, epoxides, hydroxylated compounds and drug metabolites as well as recent advances in enzyme catalyzed acylation, dehalogenation, esterification, oxidation-reduction, transamination, deamination, C-N, C-C, C-O bond formation, Baeyer-Villegar reaction and aldol as well as acyloin condensation reactions are covered. Cutting-edge topics such as directed evolution by gene shuffling and enzyme engineering to improve biocatalysts will be presented. Enzyme immobilization and reusability studies and enzymatic protection and deprotection are addressed as well'-- _cProvided by publisher.
588			_aDescription based on print version record and CIP data provided by publisher.
650		0	_aEnzymes _xBiotechnology.
650		0	_aBiocatalysis.
650		0	_aGreen chemistry.
650		7	_aTECHNOLOGY & ENGINEERING / Chemical & Biochemical. _2bisacsh
650		7	_aBiocatalysis. _2fast _0(OCoLC)fst01896571
650		7	_aEnzymes _xBiotechnology. _2fast _0(OCoLC)fst00913608
650		7	_aGreen chemistry. _2fast _0(OCoLC)fst00912867
655		4	_aElectronic books.
700	1		_aPatel, Ramesh N., _d1942-
773	0		_tWiley e-books
776	0	8	_iPrint version: _tGreen biocatalysis _dHoboken, New Jersey : John Wiley & Sons, 2016 _z9781118822296 _w(DLC) 2015047535
856	4	0	_uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=http://onlinelibrary.wiley.com/book/10.1002/9781118828083 _zWiley Online Library
880	8		_6505-01/(S _a3.7 INVERSION OF ENANTIOSELECTIVITY DRAMATICALLY IMPROVES CATALYTIC ACTIVITY3.8 FUTURE PROSPECTS; REFERENCES; Chapter 4 Green Processes for the Synthesis of Chiral Intermediates for the Development of Drugs ; 4.1 INTRODUCTION; 4.2 SAXAGLIPTIN: ENZYMATIC SYNTHESIS OF (S)-N-BOC-3-HYDROXYADAMANTYLGLYCINE; 4.3 SITAGLIPTIN: ENZYMATIC SYNTHESIS OF CHIRAL AMINE; 4.4 VANLEV: ENZYMATIC SYNTHESIS OF (S)-6-HYDROXYNORLEUCINE ; 4.5 VANLEV: ENZYMATIC SYNTHESIS OF ALLYSINE ETHYLENE ACETAL; 4.6 VANLEV: ENZYMATIC SYNTHESIS OF THIAZEPINE; 4.7 TIGEMONAM: ENZYMATIC SYNTHESIS OF (S)-Ý-HYDROXYVALINE.
907			_a.b16544742 _b2022-11-04 _c2019-11-12
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998			_ae _b2017-12-12 _cm _dz _feng _gnju _y0 _z.b16544742
999			_c691418 _d691418