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020 _a0471224901
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_qalk. paper)
020 _a9780471224907
_q(cloth ;
_qalk. paper)
020 _a0471227587
_q(electronic bk.)
020 _a9780471227588
_q(electronic bk.)
020 _a1280556463
020 _a9781280556463
020 _a9780471461180
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020 _a0471461180
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024 7 _a10.1002/0471227587
_2doi
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035 _a(OCoLC)85820194
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_z(OCoLC)814462992
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035 _a(OCoLC)ocm85820194
037 _a10.1002/0471227587
_bWiley InterScience
_nhttp://www3.interscience.wiley.com
039 9 _a201902141135
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050 4 _aQP624.5.D726
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_221
100 1 _aKnudsen, Steen.
245 1 2 _aA biologist's guide to analysis of DNA microarray data /
_cSteen Knudsen.
260 _aNew York :
_bWiley-Interscience,
_c©2002.
300 _a1 online resource (xiii, 125 pages, [8] pages of plates) :
_billustrations (some color)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references (pages 104-122).
504 _aIncludes bibliographical references and index.
505 0 0 _tHybridization --
_tAffymetrix GeneChip Technology --
_tSpotted Arrays --
_tSerial Analysis of Gene Expression (SAGE) --
_tExample: Affymetrix vs. Spotted Arrays --
_tOverview of Data Analysis --
_tBasic Data Analysis --
_tAbsolute Measurements --
_tScaling --
_tExample: Linear and Nonlinear Scaling --
_tDetection of Outliers --
_tFold Change --
_tSignificance --
_tNonparametric Tests --
_tCorrection for Multiple Testing --
_tExample I: t-Test and ANOVA --
_tExample II: Number of Replicates --
_tVisualization by Reduction of Dimensionality --
_tPrincipal Component Analysis --
_tExample 1: PCA on Small Data Matrix --
_tExample 2: PCA on Real Data --
_tCluster Analysis --
_tHierarchical Clustering --
_tK-means Clustering --
_tSelf-Organizing Maps --
_tDistance Measures --
_tExample: Comparison of Distance Measures --
_tNormalization --
_tVisualization of Clusters --
_tExample: Visualization of Gene Clusters in Bladder Cancer --
_tBeyond Cluster Analysis --
_tFunction Prediction --
_tDiscovery of Regulatory Elements in Promoter Regions --
_tExample 1: Discovery of Proteasomal Element --
_tExample 2: Rediscovery of Mlu Cell Cycle Box (MCB) --
_tIntegration of data --
_tReverse Engineering of Regulatory Networks --
_tThe Time-Series Approach --
_tThe Steady-State Approach --
_tLimitations of Network Modeling --
_tExample 1: Steady-State Model --
_tExample 2: Steady-State Model on Real Data --
_tExample 3: Steady-State Model on Real Data --
_tExample 4: Linear Time-Series Model --
_tMolecular Classifiers --
_tClassification Schemes --
_tNearest Neighbor --
_tNeural Networks --
_tSupport Vector Machine.
520 _aA Biologist's Guide to Analysis of DNA Microarray Data Steen Knudsen Microarrays are low-density arrays of DNA molecules that permit many hybridization experiments to be performed in parallel. A Biologist's Guide to Analysis of DNA Microarray Data is the first authoritative text to focus on analysis (as opposed to technology) in diverse biological and medical applications of microarrays. Written for biologists without special training in data analysis and statistics, the Guide takes over where the image analysis software that accompanies DNA array equipment typically leaves off with a file of signal intensities and fold changes compared to a control. The broad spectrum of established analysis approaches is covered, including cluster analysis, function prediction, and principal component analysis. A thorough, critical review of software programs is presented, and criteria for selecting programs are discussed. Each chapter contains a Further Reading section categorized by topic as well as a summary, and highlights numerous real examples to illustrate the key concepts.; Chapter topics include: Basic data analysis Visualization by reduction of dimensionality Cluster analysis of expression data Molecular classifiers Genotyping chips Software issues and data formats A Biologist's Guide to Analysis of DNA Microarray Data meets the needs of research professionals, students, and trainees alike for a compact yet thorough guide to analyzing microarray data.
588 0 _aPrint version record.
650 0 _aDNA microarrays.
650 2 _aOligonucleotide Array Sequence Analysis.
650 6 _aPuces à ADN.
650 7 _aDNA microarrays.
_2fast
_0(OCoLC)fst00886592
650 0 7 _aDatenanalyse.
_2swd
650 0 7 _aDNS.
_2swd
650 0 7 _aMicroarray.
_2swd
653 _aMolecular Cell Biology.
655 4 _aElectronic books.
710 2 _aJohn Wiley & Sons.
773 0 _tWiley e-books
776 0 8 _iPrint version:
_aKnudsen, Steen.
_tBiologist's guide to analysis of DNA microarray data.
_dNew York : Wiley-Interscience, ©2002
_z0471224901
_w(DLC) 2002072380
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=https://onlinelibrary.wiley.com/book/10.1002/0471227587
_zWiley Online Library
907 _a.b16536812
_b2022-11-08
_c2019-11-12
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