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015			_aGBC038342 _2bnb
016	7		_a019715477 _2Uk
020			_a9783030320041 _q(electronic bk.)
020			_a3030320049 _q(electronic bk.)
020			_z9783030320034 _q(print)
020			_z3030320030
024	7		_a10.1007/978-3-030-32004-1 _2doi
037			_acom.springer.onix.9783030320041 _bSpringer Nature
040			_aEBZ _beng _cEBZ
049			_aMAIN
050		4	_aRM300
072		7	_aMQC _2bicssc
072		7	_aMED058000 _2bisacsh
072		7	_aMQC _2thema
082	0	4	_a615.1 _223
090			_aeBook PPUKM
245	0	0	_aUnderstanding pharmacology in nursing practice / _cPauline Hood, Ehsan Khan, editors.
264		1	_aCham : _bSpringer, _c2020.
300			_a1 online resource (viii, 411 pages) : _bcolor illustrations
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
341	0		_atextual _2sapdv _3EBSCOhost
504			_aIncludes bibliographical references.
532		0	_3EBSCOhost _a'EBSCO evaluates our products based on the Web Content Accessibility Guidelines (WCAG) and the related Section 508 and EN 301 549 regulations in the US and EU. Most EBSCO products are substantially conformant with WCAG 2.2 level AA.' Source: https://connect.ebsco.com/s/article/EBSCO-VPATs?language=en_US. Last accessed April 22, 2025.
588	0		_aOnline resource; title from PDF title page (SpringerLink, viewed February 26, 2020).
505	0		_aIntro -- Preface -- Contents -- Part I: Legal and Ethical Issues -- 1: Legal and Ethical Issues Associated with Medication -- 1.1 Introduction -- 1.2 Professionalism and Accountability -- 1.3 Accountability -- 1.4 Legal Component of Accountability -- 1.5 Duty of Care -- 1.6 Safeguards in Practice -- 1.7 Consent -- 1.8 Ethical Principles -- 1.9 Summary -- 1.10 Useful Websites [Accessed 12 March 2019] -- Multiple Choice Questions -- Answers -- References -- Further Reading -- Part II: Principles of Pharmacology -- 2: Pharmacokinetics and Pharmacodynamics -- 2.1 Introduction
505	8		_a2.2 Pharmacokinetics -- 2.2.1 Absorption -- 2.2.1.1 Oesophageal Transit -- 2.2.1.2 Food -- 2.2.1.3 Gastrointestinal Motility -- 2.2.1.4 Drug Efflux Proteins -- 2.2.1.5 First-Pass Effect -- 2.2.1.6 Absorption Via Other Routes -- 2.2.2 Distribution -- 2.2.2.1 Fluid Compartments -- 2.2.2.2 Volume of Distribution -- 2.3 Drug Metabolism -- 2.3.1 Enzymatic Defence -- 2.3.2 Forms of Drug Metabolism -- 2.3.3 Phase I Metabolism -- 2.3.4 Phase II Metabolism -- 2.3.5 Phase III Metabolism -- 2.3.6 Enzyme Substrates -- 2.3.6.1 Clinical Importance of Substrate Interactions
505	8		_a2.3.7 Enzyme Inhibitors -- 2.3.8 Enzyme Inducers -- 2.4 Clearance -- 2.4.1 Renal Clearance -- 2.4.1.1 Formation of the Concentration Gradient -- 2.4.2 Liver Clearance -- 2.5 Drug Half-Life -- 2.6 Therapeutic Index -- 2.7 Pharmacokinetics: Summary -- 2.8 Pharmacodynamics -- 2.9 Ion Channels -- 2.10 Ligands -- 2.11 Ion Pumps -- 2.12 Receptor -- 2.13 Enzymes -- 2.14 Cell Membranes -- 2.15 Receptor Theory -- 2.15.1 Affinity -- 2.16 Drug Interactions with Their Target -- 2.16.1 Agonist -- 2.16.2 Antagonists -- 2.17 Categories -- 2.18 Competitive Antagonism
505	8		_a2.18.1 Non-competitive Antagonist -- 2.18.2 Partial Agonists -- 2.19 Receptor Classification -- 2.20 Summary -- Multiple Choice Questions -- Answers -- References -- 3: Drug Formulations -- 3.1 Introduction -- 3.2 Necessity for Different Dosage Forms -- 3.3 General Considerations in the Design of Dosage Forms -- 3.4 Drug Stability -- 3.5 Product Shelf Life -- 3.6 Pharmaceutical Excipients -- 3.7 Identifying Patient Reactions to Excipients in Practice -- 3.8 Summary -- 3.9 Pharmaceutical Dosage Forms -- 3.9.1 Introduction -- 3.9.2 Solid Dosage Forms -- 3.9.3 Capsules
505	8		_a3.9.4 Tablets -- 3.9.5 Compressed Tablets -- 3.9.6 Buccal or Sublingual Tablets -- 3.9.7 Extended-Release Dosage Forms -- 3.9.8 Guidance on Dosage Forms That Cannot Be Altered -- 3.9.9 Semi-solid Dosage Forms -- 3.9.9.1 Creams -- 3.9.9.2 Hydrophobic Creams (w/o) -- 3.9.9.3 Hydrophilic Creams (o/w) -- 3.9.9.4 Gels -- 3.9.9.5 Hydrophobic Gels -- 3.9.9.6 Hydrophilic Gels -- 3.9.9.7 Ointments -- 3.9.9.8 Hydrophobic Ointments -- 3.9.9.9 Water-Emulsifying Ointments -- 3.9.9.10 Hydrophilic Ointments -- 3.9.9.11 Pastes -- 3.9.10 Guidance for the Use of Semi-solid Forms
520			_aThis textbook provides a structured, informed approach to the understanding and appreciation of drug action and effect providing a detailed description and discussion of pharmacokinetics and pharmacodynamics for nurses. The text focuses and emphasizes safe prescribing and administration of medication highlighting the possible harm to patient in terms of adverse reactions. This book also includes the seldom addressed facet of pharmacotherapeutics; drug formulation as applied to practice, and adverse reactions. It informs on the medication used to manage diabetes mellitus, respiratory disease, gastrointestinal tract, the central nervous system and many other affections. Uniting these essential pharmacological processes and applying them to physiological system based medications, this work highlights issues relevant to drug interaction and important nursing responsibilities associated with administration/prescribing. The overall aim of the text is to equip the nurse with an understanding of issues related to pharmacotherapeutics that is aligned to current nursing roles and statutory requirements. .
590			_aAdded to collection customer.56279.3
650		0	_aPharmacology.
650		0	_aNursing.
655		4	_aElectronic books.
700	1		_aHood, Pauline, _eeditor.
700	1		_aKhan, Ehsan, _eeditor.
776	0	8	_iPrint version: _z3030320030 _z9783030320034
856	4	0	_3EBSCOhost _uhttps://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=2540682
907			_a.b17073303 _b2025-07-28 _c2025-07-21
942			_n0 _keBook PPUKM
998			_a1 _b2025-07-21 _cm _dz _feng _gsz _y0 _z.b17073303
999			_c673923 _d673923