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020 _a9780128172810
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020 _a9780128165720
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020 _a0128165723
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035 _a1908139
035 _a(OCoLC)1085348389
037 _a9780128172810
_bIngram Content Group
040 _aNST
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082 0 4 _a616.079
_223
100 1 _aActor, Jeffrey K.,
_eauthor.
245 1 0 _aIntroductory immunology :
_bbasic concepts for interdisciplinary applications /
_cJeffrey K. Actor.
250 _aSecond edition.
264 1 _aCham :
_bAcademic Press,
_c2019.
300 _a1 online resource. :
_bcolor illustrations
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references and index.
588 0 _aOnline resource; title from PDF title page (EBSCO, viewed Feburary 13, 2019).
505 0 _aFront Cover; Introductory Immunology: Basic Concepts for Interdisciplinary Applications; Copyright; Dedication; Contents; Preface; Acknowledgments; Chapter 1: A Functional Overview of the Immune System and Immune Components; Chapter Focus; Immune Homeostasis; Self versus Nonself; Innate and Adaptive Immunity; Anatomy of the Immune System; Cells of the Immune System; First-Line Defenders: The Myeloid Cells; Adaptive Avengers: The Lymphoid Cells; Lymphocytes; Cluster of Differentiation; Summary; Chapter 2: The Inflammatory Response; Chapter Focus; Inflammation
505 8 _aInitiation of the Inflammatory ResponseThe Role of Antibodies in Inflammation; Biological Functions of Complement; Activation and Directed Migration of Leukocytes; Pathogen Recognition and Cytokine Signaling; Feedback and Adaptation From a Distance; Pathological Consequences of the Inflammatory Response; Summary; Chapter 3: The B Lymphocyte: Antibodies and How They Function; Chapter Focus; B Lymphocytes Produce Antibodies; Structural Characteristics of Immunoglobulins; Immunoglobulin Nomenclature; Biologic Properties of Antibody Isotypes; IgD; IgM; IgG; IgA; IgE; Kinetics of Antibody Response
505 8 _aMembrane-Bound ImmunoglobulinDevelopment of B Cells; Gene Recombination; Development and Selection of Mature B Cells; Activation and Differentiation of B Cells; Summary; Chapter 4: T Lymphocytes: Ringleaders of Adaptive Immune Function; Chapter Focus; T Lymphocytes: Specific and Long-Lasting Immunity; The T Cell Receptor; T-Cell Development; Antigen Recognition by T Cells: Requirement of Major Histocompatability Molecules; The HLA Locus; MHC Class I; MHC Class II; T Lymphocyte Functions; CD4+ T-Helper Cells; Events Involved in T Lymphocyte Activation; Role of T Cells in B-Cell Activation
505 8 _aParasitic Infections (Helminths)Fungal Infections; Evasion of Immune Response; Summary; Chapter 6: Basic Disorders of Immune Function; Chapter Focus; Immunodeficiency Disorders; Genetic Basis for Primary Immunodeficiency; Innate Deficiencies; Chronic Granulomatous Disease; Leukocyte Adhesion Deficiency; Chediak-Higashi Syndrome; Complement Disorders; Innate Pattern-Recognition Receptor (PRR) Disorders; Adaptive Immune Disorders; X-Linked Agammaglobulinemia (X-LA); Selective (IgA) Deficiency; Common Variable Immunodeficiency; Hyper IgM (HIM) Disorders; DiGeorge Syndrome
520 _aIntroductory Immunology: Basic Concepts for Interdisciplinary Applications, Second Edition is a completely updated, revised and expanded resource on the immune system as a primary defense for the maintenance of health and homeostasis. The book highlights the components of the human immune system and how they work together to confer protection against pathogenic invaders. It also creates an understanding of the basis for clinical tests and immune therapeutics and their importance in identifying and treating disease states. This updated edition will strengthen the foundation required to understand the placement of immune function within clinical practice, thus allowing a basic platform to define therapeutic treatments.
590 _aMaster record variable field(s) change: 072
650 0 _aImmunology.
650 7 _aHEALTH & FITNESS / Diseases / General.
_2bisacsh
650 7 _aMEDICAL / Clinical Medicine.
_2bisacsh
650 7 _aMEDICAL / Diseases.
_2bisacsh
650 7 _aMEDICAL / Evidence-Based Medicine.
_2bisacsh
650 7 _aMEDICAL / Internal Medicine.
_2bisacsh
655 4 _aElectronic books.
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/login?url=https://search.ebscohost.com.eresourcesptsl.ukm.remotexs.co/login.aspx?direct=true&db=nlebk&AN=1908139&site=eds-live&ebv=EB&ppid=pp_Cover
880 8 _6505-00/(S
_aCytotoxic T-Cell EffectorsCD8+ T Cells; Innate Lymphocytes and Superantigens; Þe T Cells; Natural Killer T (NKT) Cells; Superantigens; Summary; Chapter 5: How We Defend Against Infectious Agents; Chapter Focus; Immune Homeostasis and Pathogenic Organisms; Major Immune Defense Mechanisms Against Pathogens; Physical Barriers to Infection; Anatomic Barrier; Physiologic Barrier; Phagocytic and Endocytic Barriers; Inflammatory Barriers; Bacterial Infections; Microbial Motifs Detected Through Pattern-Recognition Receptors; Mycobacterial Infections; Viral Infections; Human Immunodeficiency Virus
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