000			02773nam a22003738i 4500
001			CR9780511979811
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007			cr||||||||||||
008			101014s2015||||enk o ||1 0|eng|d
020			_a9780511979811 (ebook)
020			_z9780521493390 (hardback)
040			_aUkCbUP _beng _erda _cUkCbUP
050	0	0	_aRC268.4 _b.S97 2015
082	0	0	_a616.99/4042 _223
245	0	0	_aSystems biology of cancer / _cedited by Sam Thiagalingam, Boston University School of Medicine.
264		1	_aCambridge : _bCambridge University Press, _c2015.
300			_a1 online resource (xv, 531 pages) : _bdigital, PDF file(s).
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
500			_aTitle from publisher's bibliographic system (viewed on 05 Oct 2015).
505	0		_aPart 1: Introduction to modular organization of the networks of gene functions and cancer ; Part 2: Alterations in the regulatory networks of cellular and molecular events ; Part 3: Events responsible for aberrant genetic and epigenetic codes in cancer ; Part 4: Functional networks of events that modulate phenotypic manifestation of cancer ; Part 5: Current state of the evolving MMMN cancer progression models of cancer ; Part 6: Applications of comprehensive cancer progression models in the fight against cancer.
520			_aWith over 200 types of cancer diagnosed to date, researchers the world over have been forced to rapidly update their understanding of the biology of cancer. In fact, only the study of the basic cellular processes, and how these are altered in cancer cells, can ultimately provide a background for rational therapies. Bringing together the state-of-the-art contributions of international experts, Systems Biology of Cancer proposes an ultimate research goal for the whole scientific community: exploiting systems biology to generate in-depth knowledge based on blueprints that are unique to each type of cancer. Readers are provided with a realistic view of what is known and what is yet to be uncovered on the aberrations in the fundamental biological processes, deregulation of major signaling networks, alterations in major cancers and the strategies for using the scientific knowledge for effective diagnosis, prognosis and drug discovery to improve public health.
650		0	_aCancer _xGenetic aspects.
650		0	_aSystems biology.
700	1		_aThiagalingam, Sam, _d1957- _eeditor.
776	0	8	_iPrint version: _z9780521493390
856	4	0	_uhttps://doi.org/10.1017/CBO9780511979811
907			_a.b16844051 _b2020-12-22 _c2020-12-22
942			_n0
998			_a1 _b2020-12-22 _cm _da _feng _genk _y0 _z.b16844051
999			_c651749 _d651749