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020 _a9783527674411
_q(electronic bk.)
020 _a3527674411
_q(electronic bk.)
020 _a9783527674381
_q(electronic bk. ;
_qoBook)
020 _a3527674381
_q(electronic bk. ;
_qoBook)
020 _z9783527335381
020 _z3527335382 (print : alk. paper)
020 _z9783527674404 (ePub)
020 _z9783527674398 (mobi)
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029 1 _aCHNEW
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029 1 _aCHVBK
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029 1 _aGBVCP
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035 _a(OCoLC)1012487438
_z(OCoLC)1012749507
_z(OCoLC)1066459758
035 _a(OCoLC)on1012487438
039 9 _a201911011142
_bros
_y09-18-2019
_zhafiz
_wUKM UBCM Wiley MARC (363 titles).mrc
_x37
040 _aNST
_beng
_erda
_epn
_cNST
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_dIDEBK
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049 _aMAIN
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060 0 0 _aW1
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060 1 0 _aQV 745
072 7 _aMED
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082 0 4 _a615.1
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245 0 0 _aDrug selectivity :
_ban evolving concept in medicinal chemistry /
_cedited by Norbert Handler and Helmut Buschmann.
264 1 _aWeinheim, Germany :
_bWiley-VCH,
_c[2018]
264 4 _c©2018
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 1 _aMethods and principles in medicinal chemistry ;
_vv. 72
504 _aIncludes bibliographical references and index.
505 0 _aIntroduction. Polypharmacology in Drug Discovery / Oscar Méndez-Lucio, J Jesús Naveja, Hugo Vite-Caritino, Fernando D Prieto-Martínez, José L Medina-Franco -- Selectivity of Marketed Drugs. Kinase Inhibitors / Peng Wu, Michael Givskov, Thomas E Nielsen -- Repositioning of Drug -- New Indications for Marketed Drugs / Ren Kong, Stephen T Wong -- Discovery Technologies for Drug Repurposing / Naiem T Issa, Stephen W Byers, Sivanesan Dakshanamurthy -- Unselective Drugs in Drug Discovery. Personalized Medicine / Christian Noe, Volker Baumann -- Drug Discovery Strategies for the Generation of Multitarget Ligands against Neglected Tropical Diseases / Annachiara Gandini, Federica Prati, Elisa Uliassi, Maria L Bolognesi -- Designing Approaches to Multitarget Drugs / Luca Costantino, Daniela Barlocco -- The Linker Approach / Daniel Merk, Manfred Schubert-Zsilavecz -- Merged Multiple Ligands / Hongming Chen, Udo Bauer, Ola Engkvist -- Pharmacophore Generation for Multiple Ligands / Norbert Handler -- Cellular Assays / Ye Fang -- Therapeutic Areas for Designed Multiple Ligands. Developing Serotonergic Antidepressants Acting on More Than the Serotonin Transporter / Gerard J Marek -- Multiple Ligands Targeting the Angiotensin System for Hypertension / Agustin Casimiro-Garcia -- Multiple Peroxisome Proliferator-Activated Receptor-Based Ligands / Dmytro Kukhtar, Miquel Mulero, Raul Beltrán-Debón, Cristina Valls, Gerard Pujadas, Santiago Garcia-Vallve -- Antibiotics / Jean-Philippe Surivet, Philippe Panchaud -- Multiple Ligands in Neurodegenerative Diseases / Julien Lalut, Christophe Rochais, Patrick Dallemagne.
588 0 _aVendor-supplied metadata.
650 0 _aDrugs
_xEffectiveness.
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aDrugs
_xEffectiveness.
_2fast
_0(OCoLC)fst00898808
650 1 2 _aDrug Design.
650 2 2 _aChemistry, Pharmaceutical.
650 2 2 _aPharmaceutical preparations.
655 4 _aElectronic books.
655 0 _aElectronic book.
700 1 _aHandler, Norbert,
_eeditor.
700 1 _aBuschmann, Helmut,
_eeditor.
773 0 _tWiley e-books
830 0 _aMethods and principles in medicinal chemistry ;
_vv. 72.
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1002/9783527674381
_zWiley Online Library
907 _a.b16755303
_b2022-10-20
_c2019-11-12
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