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008 170308s2015||||enk o ||1 0|eng|d
020 _a9781139012751 (ebook)
020 _z9781107013841 (hardback)
035 _a(UkCbUP)CR9781139012751
039 9 _y03-08-2017
_zhafiz
040 _aUkCbUP
_beng
_erda
_cUkCbUP
050 0 0 _aQH438.5
_b.S97 2015
082 0 0 _a576.5
_223
245 0 0 _aSystems Genetics :
_bLinking Genotypes and Phenotypes /
_cedited by Florian Markowetz, Michael Boutros.
264 1 _aCambridge :
_bCambridge University Press,
_c2015.
300 _a1 online resource (268 pages) :
_bdigital, PDF file(s).
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
490 0 _aCambridge Series in Systems Genetics
500 _aTitle from publisher's bibliographic system (viewed on 07 Mar 2017).
520 _aWhereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies.
650 0 _aPhenotype
650 0 _aGenetics
650 0 _aFunctional genomics
700 1 _aMarkowetz, Florian,
_eeditor.
700 1 _aBoutros, Michael,
_eeditor.
776 0 8 _iPrint version:
_z9781107013841
830 0 _aCambridge Series in Systems Genetics.
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1017/CBO9781139012751
907 _a.b1644159x
_b2022-11-01
_c2019-11-12
942 _n0
914 _avtls003618450
998 _anone
_b2017-08-03
_cm
_da
_feng
_genk
_y0
_z.b1644159x
999 _c617375
_d617375