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020 _a9780128021125
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020 _a0128021020
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020 _a9780128021026
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020 _z9780128051238
020 _z9780128021026
024 3 _a9780128021026
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035 _a(OCoLC)932124529
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035 _a(OCoLC)ocn932124529
039 9 _y12-21-2016
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049 _aMAIN
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082 0 4 _a543/.65
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100 1 _aGhosh, Pradip K.,
_eauthor.
245 1 0 _aIntroduction to protein mass spectrometry /
_cPradip Kumar Ghosh.
264 1 _aLondon, UK :
_bAcademic Press is an imprint of Elsevier,
_c[2015]
264 4 _cò016
300 _a1 online resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
500 _aIncludes index.
505 0 _aTitle page; Table of Contents; Copyright page; Dedication; Preface; Chapter 1: Introduction; Chapter 2: Sample Preparation and Ionization for Mass Spectrometry; 2.1 Separation of protein mixtures; 2.2 Multidimensional separations; 2.3 Proteolysis; 2.4 Ionization of proteins and peptides; Chapter 3: Instruments; 3.1 Mass analysis; 3.2 Some examples of instruments; Chapter 4: Mass Spectrometry of Peptides and Proteins; 4.1 Proteins; 4.2 Alternative analysis methods; 4.3 Quantitation; 4.4 Peptide fragmentation: Experiments; 4.5 Data mining scheme for identifying peptide structural motifs.
505 8 _a4.6 Peptide fragmentation: mechanism4.7 Possible pathways in the competition model; 4.8 Studying post translational modifications; 4.9 Chemical cross-linking/mass spectrometry; 4.10 Manual de novo sequencing of peptides; Chapter 5: Examples from Biological Applications; 5.1 Mapping intact protein isoforms using top-down proteomics; 5.2 Quantitative analysis of intact apolipoproteins in human HDL; 5.3 Rapid sequence analysis of some conotoxins -- combination of de novo, bottom-up methods; 5.4 Mass spectrometry of ribosomes; 5.5 Proteins in Purkinje cell post-synaptic densities.
505 8 _a5.6 Neurexin-LRRTM2 interaction effect in synapse formation5.7 Rapid analysis of human plasma proteome -- an IMS-IMS-MS application; 5.8 Topology of two transient virus capsid assembly intermediates; 5.9 Mass spectrometry of intact V-type ATPases reveals bound lipids and the effects of nucleotide binding; 5.10 Mass spectrometric imaging of biological material; Chapter 6: Mass Spectrometry-Based Bioinformatics; 6.1 Peptides to proteins; 6.2 MS/MS fragments to peptides to proteins; 6.3 Data-dependent acquisition; 6.4 Targeted acquisition covering SRM and PRM; 6.5 Data-independent acquisition.
520 8 _aUnlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made.
588 0 _aOnline resource; title from PDF title page (ScienceDirect, viewed December 15, 2015).
590 _aElsevier
_bScienceDirect All Books
650 0 _aMass spectrometry.
650 7 _aSCIENCE
_xChemistry
_xAnalytic.
_2bisacsh
650 7 _aMass spectrometry.
_2fast
_0(OCoLC)fst01011435
655 4 _aElectronic books.
776 0 8 _iPrint version:
_aGhosh, Pradip Kumar.
_tIntroduction to Protein Mass Spectrometry.
_d: Elsevier Science, ò015
_z9780128051238
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780128021026
907 _a.b1640175x
_b2022-11-03
_c2019-11-12
942 _n0
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998 _ae
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