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020 _z9780123948038
_q(print)
020 _z0123948037
_q(print)
029 1 _aDEBBG
_bBV043216606
035 _a(OCoLC)927437815
035 _a(OCoLC)ocn927437815
039 9 _y12-21-2016
_zhafiz
_wmetacoll.MYUKM.updates.D20160920.T210208.sdallbooks.1 (perolehan)hafizupload21122016.mrc
_x242
040 _aOPELS
_beng
_erda
_epn
_cOPELS
_dMMU
_dUIU
_dOCLCQ
_dDEBBG
_dVT2
_dVLB
049 _aMAIN
050 4 _aQP517.C45
060 4 _aQU 375
082 0 4 _a571.7/4
_223
100 1 _aKramer, IJsbrand M.,
_eauthor.
245 1 0 _aSignal transduction /
_cIJsbrand M. Kramer.
250 _aThird edition.
264 1 _aLondon :
_bElsevier/Academic Press,
_c[2016]
264 4 _cò016
300 _a1 online resource :
_billustrations (chiefly color)
336 _atext
_btxt
_2rdacontent
336 _astill image
_bsti
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
504 _aIncludes bibliographical references.
505 0 _aPrologue : signal transduction from an historical perspective -- An introduction to signal transduction -- Regulation of muscle contraction by adrenoceptors -- Cholinergic signaling and muscle contraction -- Sensory signal processing; visual transduction and olfaction -- Intracellular calcium -- Bringing the signal into the nucleus : regulation of gene expression -- Nuclear receptors -- Protein kinase c in oncogenic transformation and cell polarity -- Regulation of cell proliferation by receptor tyrosine protein kinases -- Signal transduction to and from adhesion molecules -- WNT signaling and the regulation of cell adhesion and differentiation -- Activation of the innate immune system : the toll-like receptor-4 and signaling through ubiquitinylation -- Chemokines and traffic of white blood cells -- Activating the adaptive immune system : role of non-receptor tyrosine kinases -- Signaling through the insulin receptor : phosphoinositide 3-kinases and AKT -- TGF[beta] and signaling through receptor serine/threonine protein kinases -- Protein phosphatases -- Cell fate determination by notch.
520 _a'A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor -ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.'--Page 4 of cover.
588 0 _aOnline resource; title from PDF title page (ScienceDirect, viewed November 4, 2015).
590 _aElsevier
_bScienceDirect All Books
650 0 _aCellular signal transduction.
650 1 2 _aSignal transduction.
650 6 _aTransduction du signal cellulaire.
650 7 _aSCIENCE
_xLife Sciences
_xCell Biology.
_2bisacsh
650 7 _aCellular signal transduction.
_2fast
_0(OCoLC)fst00850288
650 1 7 _aSignalen.
_2gtt
655 4 _aElectronic books.
776 0 8 _iErscheint auch als:
_nDruck-Ausgabe
_aKramer, Ijsbrand M.
_tSignal transduction
_w(DE-604)BV043329994
856 4 0 _uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780123948038
907 _a.b16401608
_b2022-11-02
_c2019-11-12
942 _n0
914 _avtls003614265
998 _ae
_b2016-08-12
_cm
_dz
_feng
_genk
_y0
_z.b16401608
999 _c613546
_d613546