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008			161221t20152015ne ao ob 001 0 eng d
020			_a9780128005446 _q(e-book)
020			_a0128005440 _q(e-book)
020			_a0128001348
020			_a9780128001349
020			_z9780128001349
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035			_a(OCoLC)912312563 _z(OCoLC)907521685 _z(OCoLC)907610327
035			_a(OCoLC)ocn912312563
037			_a768352 _bMIL
039		9	_y12-21-2016 _zhafiz _wmetacoll.MYUKM.updates.D20160920.T210208.sdallbooks.1 (perolehan)hafizupload21122016.mrc _x188
040			_aE7B _beng _erda _epn _cE7B _dOCLCO _dEBLCP _dDEBSZ _dIDEBK _dOPELS _dCOO _dYDXCP _dCDX _dOCLCF _dOCLCQ
049			_aMAIN
050		4	_aQP185 _b.S745 2015eb
066			_c(S
082	0	4	_a612.35 _223
245	0	0	_aStellate cells in health and disease / _cedited by Chandrashekhar R. Gandhi, Massimo Pinzani.
264		1	_aAmsterdam [Netherlands] : _bAcademic Press, _c2015.
264		4	_cò015
300			_a1 online resource (335 pages) : _billustrations (some color), photographs
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
504			_aIncludes bibliographical references at the end of each chapters and index.
505	0		_aFront Cover; Stellate Cells in Health and Disease; Copyright Page; Dedication; Contents; List of Contributors; Foreword; What have we learned?; The outlook for anti-fibrotic treatment; References; Preface; 1 History and Early Work; 1.1 Discovery of Hepatic Stellate Cells; 1.2 HSCs and Vitamin A Homeostasis; 1.3 Morphological Characteristics of HSCs; 1.4 HSCs and Liver Fibrosis; 1.5 Isolation and Culture of HSCs; 1.6 Activation and Transdifferentiation of HSCs; 1.7 Markers for HSCs; 1.8 Perspective; References; 2 Hepatic Stellate Cell Culture Models; 2.1 Isolation of Hepatic Stellate Cells.
505	8		_a2.2 Single Cell Culture2.3 In Vitro- Versus In Vivo-Activated HSCs; 2.4 Single Cell Culture and 2D: Importance of Adhesion, Arg-Gly-Asp, and Matrix Components; 2.5 HSC Co-Cultures with Kupffer Cells, Hepatocytes, LSEC, HCC, and CC Cells; 2.6 In Vitro 3D Culture Systems; 2.7 Conclusions; References; 3 Hepatic Fibrosis: A Global Clinical Problem; 3.1 Introduction; 3.2 Chronic Viral Hepatitis; 3.2.1 Alcohol-induced liver fibrosis; 3.3 NAFLD and NASH; 3.4 Autoimmune Hepatitis, Primary Biliary Cirrhosis, and Primary Sclerosing Cholangitis; 3.5 Etiology-Driven Liver Fibrosis; 3.5.1 Perspectives.
505	8		_6880-01 _a6.2.1 Contribution of HSCs to liver fibrosis6.2.1.1 HSCs/Myofibroblasts are the primary target of anti-fibrotic therapy; 6.2.1.2 Reversibility of liver fibrosis; 6.2.1.3 Inactivation of HSCs (iHSCs); 6.2.2 Other functions of HSCs; 6.2.2.1 Distinct functions of senescent HSCs; 6.2.2.2 HSC as regulatory bystanders; 6.2.2.3 HSCs as regulators of hepatocellular damage; 6.2.2.4 The role of HSCs in liver regeneration; 6.3 Portal Fibroblasts; 6.3.1 Characterization of PFs; 6.4 Epithelial-to-Mesenchymal Transition; 6.5 Perspective; References; 7 Matrix Metalloproteinases and Their Inhibitors.
520			_aStellate Cells in Health and Disease is a comprehensive reference providing the most up-to-date knowledge and perspectives on the function of stellate cells affecting the liver and other organs. The text presents comprehensive coverage of their already established role in hepatic fibrosis along with the newer emerging evidence for stellate cell participation in the liver cell (hepatocyte) survival and regeneration, hepatic immunobiology, transplant tolerance, and liver cancer. Chapters describe both animal and human research and the relevance of findings from animal research to human pathophysiology, and also contain sections on future directions which will be of special interest to basic and clinical researchers working on liver fibrosis, hepatic biology, and pathobiology.
588	0		_aOnline resource; title from PDF title page (ebrary, viewed April 24, 2015).
590			_aElsevier _bScienceDirect All Books
650		0	_aKupffer cells.
650		7	_aKupffer cells. _2fast _0(OCoLC)fst00989375
655		4	_aElectronic books.
700	1		_aGandhi, Chandrashekhar, _eeditor.
700	1		_aPinzani, Massimo, _eeditor.
776	0	8	_iPrint version: _tStellate cells in health and disease. _dAmsterdam, [Netherlands] : Academic Press, ò015 _hxix, 314 pages _z9780128001349
856	4	0	_uhttps://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780128001349
880	8		_6505-01/(S _a4.4 New and Emerging Pathways of HSC Activation4.5 Conclusions; References; 5 Cytokine Production and Signaling in Stellate Cells; 5.1 Introduction; 5.2 Platelet-Derived Growth Factor; 5.3 Angiogenic Cytokines; 5.4 TGF-Ý Superfamily; 5.5 Chemokines; 5.6 Tumor Necrosis Factor Superfamily; 5.7 Interleukins and Interferons; 5.8 Adipokines and Other Cytokines Related to Metabolism; 5.9 Osteopontin; 5.10 Perspective; References; 6 Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition; 6.1 Introduction; 6.2 Hepatic Stellate Cells.
907			_a.b16401062 _b2022-11-02 _c2019-11-12
942			_n0
914			_avtls003614211
998			_ae _b2016-08-12 _cm _dz _feng _gne _y0 _z.b16401062
999			_c613492 _d613492