000			03046cam a2200397 i 4500
005			20250919004410.0
008			150512t20152015nyua 000 0 eng
020			_a9780815342441 (paperback) _cRM278.62
020			_a0815342446 (paperback)
039		9	_a201509231244 _bruzini _c201509231242 _druzini _y05-12-2015 _zfashihah
040			_aUKM _erda
090			_aQH604.2.L732c 2015 9
090			_aQH604.2 _b.L732c 2015 9
100	1		_aLim, Wendell, _eauthor.
245	1	0	_aCell signaling : _bprinciples and mechanisms / _cWendell Lim, Bruce Mayer, Tony Pawson.
264		1	_aNew York : _bGarland Science, Taylor & Francis Group, _c2015.
264		4	_c©2015.
300			_axvi, 400 pages : _bcolor illustrations ; _c28 cm. + _e1 poster (colour illustrations, both sides ; 71 x 53 cm.)
336			_atext _2rdacontent
337			_aunmediated _2rdamedia
338			_avolume _2rdacarrier
504			_aIncludes bibliographical references and index.
505	0		_aIntroduction to cell signaling -- Principles and mechanisms of protein interactions -- Signaling enzymes and their allosteric regulation -- Role of post-translational modifications in signaling -- Subcellular localization of signaling molecules -- Second messengers: small signaling mediators -- Membranes, lipids, and enzymes that modify them -- Information transfer across the membrane -- Regulated protein degradation -- Modular architecture and evolution of signaling proteins -- Information processing by signaling devices and networks -- How cells make decisions -- Methods for studying signaling proteins and networks.
520			_a'Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are'wired' into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods'-- _cProvided by publisher.
650		0	_aCellular signal transduction.
650		0	_aCell interaction.
700	1		_aMayer, Bruce, _eauthor.
700	1		_aPawson, T, _eauthor.
907			_a.b16142512 _b2019-11-12 _c2019-11-12
942			_c01 _n0 _kQH604.2.L732c 2015 9
914			_avtls003586175
991			_aFakulti Farmasi,KKL
998			_ad _b2015-12-05 _cm _da _feng _gnyu _y0 _z.b16142512
999			_c592292 _d592292