000 02969cam a2200421 i 4500
005 20250919004410.0
008 150512s2013 enka b 001 0 eng
020 _a9780199697397 (pbk.)
_cRM322.14
020 _a0199697396 (pbk.)
039 9 _a201509141026
_bruzini
_c201507091142
_drajak
_c201506240933
_druzini
_c201506161205
_druzini
_y05-12-2015
_zfashihah
040 _aUKM
_erda
090 _aQV744.P314i 2013 9
090 _aQV744
_b.P314i 2013 9
100 1 _aPatrick, Graham L.,
_eauthor
245 1 3 _aAn introduction to medicinal chemistry /
_cGraham L. Patrick.
250 _aFifth edition.
264 1 _aOxford :
_bOxford University Press,
_c2013.
264 4 _c©2013.
300 _axxiii, 789 pages :
_billustrations (some colour) ;
_c25 cm.
336 _atext
_2rdacontent
337 _aunmediated
_2rdamedia
338 _avolume
_2rdacarrier
504 _aIncludes bibliographical references and index.
505 0 _aDrugs and drug targets - an overview -- Drug targets : structure and function -- Protein structure and function -- Enzymes: structure and function -- Receptors: structure and function -- Receptors and signal transduction -- Nucleic acids: structure and function -- Pharmacodynamics and pharmacokinetics -- Enzymes as drug targets -- Receptors as drug targets -- Nucleic acids as drug targets -- Miscellaneous drug targets -- Pharmacokinetics and related topics -- Statins -- Drug discovery, design, and development -- Drug discovery: finding a lead -- Drug design: optimizing target interactions -- Drug design: optimizing access to the target -- Getting the drug to market -- The design of ACE inhibitors -- Artemisinin and related antimalarial drugs -- The design of oxamniquine -- Tools of the trade -- Combinatorial synthesis -- Computers in medicinal chemistry -- Quantitative structure-activity relationships (QSAR) -- De novo design of a thymidylate synthase inhibitor -- Selected topics in medicinal chemistry -- Antibacterial agents -- Antiviral agents -- Anticancer agents -- Cholinergics, anticholinergics, and anticholinesterases -- Drugs acting on the adrenergic nervous system -- Opioid analgesics -- Antiulcer agents -- Steroidal anti-inflammatory agents -- Design of a novel antidepressant.
520 8 _aThis volume provides an introduction to medicinal chemistry. It covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
650 2 _aChemistry, Pharmaceutical.
650 2 _aDrug Design.
650 2 _aPharmacokinetics.
650 7 _aPharmaceutical chemistry.
_2fast
_0(OCoLC)fst01060115
650 7 _aFarmacochemie.
_2gtt
907 _a.b1614241x
_b2019-11-12
_c2019-11-12
942 _c01
_n0
_kQV744.P314i 2013 9
914 _avtls003586161
991 _aFakulti Farmasi,KKL
998 _ad
_b2015-12-05
_cm
_da
_feng
_genk
_y0
_z.b1614241x
999 _c592282
_d592282