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020 _z1606506374
020 _a9781606506363
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020 _z9780791860243
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040 _aNYMPP
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090 _aR857.B54R847 3
090 _aR857.B54
_bR847 3
100 1 _aRushworth, Jo V.,
_eauthor.
245 1 0 _aImpedimetric biosensors for medical applications :
_bcurrent progress and challenges /
_cJo V. Rushworth, Natalie A. Hirst, Jack A. Goode, Douglas J. Pike, Asif Ahmed, Paul A. Millner.
246 1 8 _ispine title :
_aBiomedical and nanomedical technologies.
264 1 _aNew York, NY :
_bASME Press :
_bMomentum Press,
_c[2013].
264 4 _c©2013.
300 _a1 online resource (70 pages) :
_billustrations ;
_c24 cm.
336 _atext
_2rdacontent
337 _acomputer
_2rdamedia
338 _aonline resource
_2rdacarrier
490 1 _aBiomedical and nanomedical technologies.
504 _aIncludes bibliographical references : (pages 57-70).
505 0 _a1. Introduction and scope.
505 0 _a2. Biosensors -- 2.1 Brief history of biosensor development -- 2.2 Applications of biosensors -- 2.3 Biosensor architecture, an overview -- 2.4 Biorecognition element -- 2.5 Transducer element -- 2.6 Summary.
505 0 _a3. Electrochemical impedance spectroscopy -- 3.1 Brief history of the development of impedimetric biosensors -- 3.2 An overview of impedance -- 3.3 Principles of impedimetric sensing -- 3.4 Presenting and analysing impedance data.
505 0 _a4. Fabrication of impedimetric biosensors -- 4.1 Electrode design and materials -- 4.2 Bioreceptor tethering to transducer surfaces.
505 0 _a5. Commercializing impedimetric biosensors: from laboratory to field -- 5.1 Components of a point-of-care diagnostic device -- 5.2 From research to point-of-care -- 5.3 Sample delivery & processing -- 5.4 Sensor regeneration -- 5.5 Barriers to commercialisation.
505 8 _a6. Case studies of impedimetric biosensors for medical applications -- 6.1 Whole cells and pathogenic microorganisms -- 6.2 Protein and peptide biomarkers of disease -- 6.3 Small molecules.
505 0 _a7. Conclusions and future perspectives.
505 0 _a8. Author biographies -- References.
520 3 _aIn this monograph, the authors discuss the current progress in the medical application of impedimetric biosensors, along with the key challenges in the field. First, a general overview of biosensor development, structure and function is presented, followed by a detailed discussion of impedimetric biosensors and the principles of electrochemical impedance spectroscopy. Next, the current state-of-the art in terms of the science and technology underpinning impedance-based biosensors is reviewed in detail. The layer- by-layer construction of impedimetric sensors is described, including the design of electrodes, their nano-modification, transducer surface functionalisation and the attachment of different bioreceptors. The current challenges of translating lab-based biosensor platforms into commercially-available devices that function with real patient samples at the POC are presented; this includes a consideration of systems integration, microfluidics and biosensor regeneration. The final section of this monograph describes case studies of successful impedance-based biosensors for the detection of a range of analytes from small molecules up to whole microorganisms. Finally, the authors put forward future perspectives for the clinical applications of impedimetric biosensors.
650 0 0 _aBiosensors.
650 0 0 _aImpedance spectroscopy.
700 1 _aHirst, Natalie A.,
_eauthor.
700 1 _aGoode, Jack A.,
_eauthor.
700 1 _aPike, Douglas J.,
_eauthor.
700 1 _aAhmed, Asif,
_eauthor.
700 1 _aMillner, Paul A.,
_eauthor.
830 0 _aBiomedical and nanomedical technologies.
856 4 0 _3ASME
_uhttp://ebooks.asmedigitalcollection.asme.org/book.aspx?bookid=844.
856 4 0 _3ASME
_uhttp://dx.doi.org/10.1115/1.860243.
856 4 0 _3Ebook Library
_uhttp://public.eblib.com/choice/publicfullrecord.aspx?p=1481266.
856 4 0 _3EBSCOhost
_uhttp://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=653952.
856 4 0 _3Safari Books Online
_uhttp://proquest.safaribooksonline.com/?fpi=9781606506363
856 4 0 _uhttp://www.momentumpress.net/
856 4 _uhttp://proquest.tech.safaribooksonline.de/9781606506363
_3Volltext
907 _a.b16118066
_b2019-11-12
_c2019-11-12
942 _c01
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_kR857.B54R847 3
914 _avtls003583505
990 _arab
991 _aFakulti Kejuruteraan dan Seni Bina
998 _al
_b2015-10-04
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_y0
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999 _c590766
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