000			03675nam a2200409 i 4500
005			20250919002759.0
008			150320s2015 gw a b 001 0 eng
020			_a9783527336081 (hd.bd. : alk. paper) _cRM708.70
020			_a3527336087 (hd.bd. : alk. paper)
039		9	_a201505271238 _batika _c201505211242 _dhamudah _y03-20-2015 _zhamudah
040			_aNLM _beng _erda _cNLM _dOHX _dUKMGB _dCUD _dYDXCP _dBTCTA _dBDX _dGSU _dUKM _erda
090			_aRA1211.P735
090			_aRA1211 _b.P735
245	1	0	_aPredictive toxicology : _bfrom vision to reality / _cedited by Friedlieb Pfannkuch and Laura Suter-Dick.
264		1	_aWeinheim : _bWiley-VCH, _c[2015]
300			_axxv, 404 pages : _billustrations.
336			_atext _btxt _2rdacontent
337			_aunmediated _bn _2rdamedia
338			_avolume _bnc _2rdacarrier
490	1		_aMethods and principles in medicinal chemistry ; _vvolume 64.
504			_aIncludes bibliographical references and index.
505	0		_aIntroduction to Predictive Toxicology Tools and Methods / Laura Suter-Dick and Friedlieb Pfannkuch -- In silico toxicology : Current Approaches and Future Perspectives to Predict Toxic Effects with Computational Tools / Thomas Steger-Hartmann -- In silico approaches: Data Management : Bioinformatics / Arnd Brandenburg, Hans Gmuender, and Timo Wittenberger -- Role of Modeling and Simulation in Toxicology Prediction / Antje-Christine Walz, Hans Peter Grimm, Christophe Meille, Antonello Caruso, Neil Parrott, and Thierry Lav-- Genomic Applications for Assessing Toxicities of Liver and Kidney Injury / Philip Hewitt and Esther Johann -- Use of Toxicogenomics for Mechanistic Characterization of Hepatocarcinogens in Shorter Term Studies / Heidrun Ellinger-Ziegelbauer -- Discovery and Application of Novel Biomarkers / Timothy W. Gant, Emma L. Marczylo, and Martin O. Leonard -- Predictive Toxicology: Genetics, Genomics, Epigenetics, and Next-Generation Sequencing in Toxicology / Tobias Heckel and Laura Suter-Dick -- Biomarkers as Tools for Predictive Safety Assessment: Novel Markers of Drug-Induced Kidney Injury / Angela Mally -- The Use of Renal Cell Culture for Nephrotoxicity Investigations / Anja Wilmes and Paul Jennings -- The Zebrafish Model in Toxicology / Natalie Mesens -- Predictive Method Development: Challenges for Cosmetics and Genotoxicity as a Case Study / Gladys Ouraogo, Fabrice Nesslany, Sophie Simar, Smail Talahari, Doris Lagache, Eric Vercauteren, Lauren Nakab, Astrid Mayoux, Brigitte Faquet, and Nicole Flamand -- Using Pluripotent Stem Cells and Their Progeny as an in vitro Model to Assess (Developmental) Neurotoxicity / Lisa Hoelting, Marcel Leist, and Luc Stoppini -- Stem Cell-Based Methods for Identifying Developmental Toxicity Potential / Jessica A. Palmer, Robert E. Burrier, Laura A. Egnash, and Elizabeth L.R. Donley -- Immunogenicity of Protein Therapeutics: Risk Assessment and Risk Mitigation / Harald Kropshofer -- Regulatory Aspects / Beatriz Silva Lima.
650		0	_aToxicology.
650		0	_aDrugs _xToxicity testing.
650		0	_aDrug development _xSafety measures.
700	1		_aPfannkuch, Friedlieb, _eeditor.
700	1		_aSuter-Dick, Laura, _eeditor.
830			_aMethods and principles in medicinal chemistry ; _vvolume 64.
907			_a.b1609928x _b2019-11-12 _c2019-11-12
942			_c01 _n0 _kRA1211.P735
914			_avtls003581436
990			_anab
991			_aFakulti Sains dan Teknologi
998			_at _b2015-07-03 _cm _da _feng _ggw _y0 _z.b1609928x
999			_c588985 _d588985