| 000 | 02987cam a2200457 a 4500 | ||
|---|---|---|---|
| 005 | 20250919000621.0 | ||
| 008 | 140915s2012 enka b 001 0 eng | ||
| 020 |
_a9781420092387 (Cloth) _cRM554.40 |
||
| 020 | _a1420092383 (Cloth) | ||
| 039 | 9 |
_a201409261153 _bzainol _y09-15-2014 _zfida |
|
| 040 |
_dUKM _erda |
||
| 090 | _aQV744.D794 2012 9 | ||
| 090 |
_aQV744 _b.D794 2012 9 |
||
| 245 | 0 | 0 |
_aDrug stereochemistry : _banalytical methods and pharmacology / _cKrzysztof J{u2BE2}zwiak, W. John Lough, Irving W. Wainer. |
| 250 | _a3rd ed. | ||
| 264 | 1 |
_aLondon ; _aNew York : _bInforma Healthcare, _c2012. |
|
| 300 |
_ax, 322 p. : _billustration ; _c24 cm. |
||
| 336 |
_atext _2rdacontent |
||
| 337 |
_aunmediated _2rdamedia |
||
| 338 |
_avolume _2rdacarrier |
||
| 490 | 1 |
_aDrugs and the pharmaceutical science series ; _vv. 211 |
|
| 504 | _aIncludes bibliographical references and index. | ||
| 520 | _a'Updated to reflect modern advances in the techniques and methodology of drug stereochemistry, the Third Edition comprehensively presents all aspects of chiral drugs from scientific, academic, governmental, industrial, and clinical points of view. This stand-alone text covers the lifespan of stereochemistry, from its early history, including an overview of terms and concepts, to the current drug development process, legal and regulatory issues, and the new stereoisomeric drugs. New topics in the Third Edition include: The use of enzymes in the synthesis and resolution of enantiometrically pure compounds in drug discovery; How stereochemistry impacts decisions made in the Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) stages of drug discovery; A chapter on pharmacokinetics and pharmacodynamics that discusses the issues faced during the final stages of the drug development process; The impact of International Conference on Harmonisation on the use of single isomer drugs; Racemic switches; The concept of molecular chiral recognition and how it affects the separation and behavior of stereochemically pure drugs; A chapter on the legal perspectives of patent issues surrounding racemic switches and the marketing of single enantiomer switches'--Provided by publisher. | ||
| 650 | 2 |
_aChemistry, Pharmaceutical _xmethods. |
|
| 650 | 2 | _aMolecular Conformation. | |
| 650 | 2 | _aStereoisomerism. | |
| 650 | 7 |
_aPharmaceutical chemistry. _2fast _0(OCoLC)fst01060115 |
|
| 655 | 7 |
_aMethods. _2fast _0(OCoLC)fst01423850 |
|
| 700 | 1 |
_aJozwiak, Krzysztof, _d1971- _eeditor |
|
| 700 | 1 |
_aLough, W. J. _q(W. John) _eeditor |
|
| 700 | 1 |
_aWainer, Irving W. _eeditor |
|
| 830 | 0 |
_aDrugs and the pharmaceutical sciences ; _vv. 211. |
|
| 907 |
_a.b15989537 _b2019-11-12 _c2019-11-12 |
||
| 942 |
_c01 _n0 _kQV744.D794 2012 9 |
||
| 914 | _avtls003569193 | ||
| 990 | _azr | ||
| 991 | _aFakulti Farmasi, KKL | ||
| 998 |
_ad _b2014-02-09 _cm _da _feng _genk _y0 _z.b15989537 |
||
| 999 |
_c578278 _d578278 |
||