000 02560nam a22004454a 4500
005 20250918153251.0
007 co ugu||||||||
008 120424s2011 flua b 001 0 eng
010 _a2010-025741
020 _a9781439816783 (hbk)
_cRM259.12
020 _a1439816786 (hbk)
039 9 _a201205301057
_bbaiti
_c201205220905
_drahah
_c201204241628
_drahah
_y04-24-2012
_zrahah
040 _aUKM
090 _aQH324.2.M337
090 _aQH324.2
_b.M337
100 1 _aMacCuish, John D.
245 1 0 _aClustering in bioinformatics and drug discovery /
_cJohn D. MacCuish, Norah E. MacCuish.
260 _aBoca Raton, FL :
_bCRC Press,
_cc2011.
300 _a214 p. :
_bill. ;
_c25 cm. +
_e1 DVD (4 3/4 in.)
490 0 _aChapman & Hall/CRC mathematical and computational biology series
500 _aBook is a accompanied by one computer optical discs entitled ' clustering in bioinformatics and drug discovery' bearing the same call number and available at bahagian media.
504 _aIncludes bibliographical references and index.
505 8 _a(Publisher-supplied data) Introduction -- Data -- Clustering Forms -- Partitional Algorithms -- Cluster Sampling Algorithms - Hierarchical Algorithms -- Hybrid Algorithms -- Asymmetry -- Ambiguity -- Validation -- Large Scale and Parallel Algorithms.
520 _a'This book presents an introduction to cluster analysis and algorithms in the context of drug discovery clustering applications. It provides the key to understanding applications in clustering large combinatorial libraries (in the millions of compounds) for compound acquisition, HTS results, 3D lead hopping, gene expression for toxicity studies, and protein reaction data. Bringing together common and emerging methods, the text covers topics peculiar to drug discovery data, such as asymmetric measures and asymmetric clustering algorithms as well as clustering ambiguity and its relation to fuzzy clustering and overlapping clustering algorithms'--Provided by publisher.
650 0 _aBioinformatics
_xMathematics.
650 0 _aDrug development.
650 0 _aCluster analysis.
650 0 _aComputational Biology.
650 1 2 _aCluster Analysis.
650 1 2 _aDrug Discovery
_xmethods.
650 2 2 _aComputational Biology.
700 1 _aMacCuish, Norah E.
907 _a.b15340442
_b2021-05-28
_c2019-11-12
942 _c01
_n0
_kQH324.2.M337
914 _avtls003498283
990 _abaiti
991 _aFakulti Sains & Teknologi
998 _at
_b2012-11-04
_cm
_da
_feng
_gflu
_y0
_z.b15340442
999 _c517819
_d517819