| 000 | 02444cam a2200313 a 4500 | ||
|---|---|---|---|
| 005 | 20250918153154.0 | ||
| 008 | 120416s2011 njua b 001 0 eng | ||
| 020 |
_a9780471771517 (cloth) _cRM348.10 |
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| 020 | _a0471771511 (cloth) | ||
| 039 | 9 |
_a201206211114 _bruzini _c201205021254 _dyusri _y04-16-2012 _zrazalis |
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| 040 | _aUKM | ||
| 090 | _aQU475.R481 2011 9 | ||
| 090 |
_aQU475 _b.R481 2011 9 |
||
| 245 | 0 | 0 |
_aRNA interference : _bapplication to drug discovery and challenges to pharmaceutical development / _cedited by Paul H. Johnson. |
| 260 |
_aHoboken, N.J. : _bWiley, _cc2011. |
||
| 300 |
_axiv, 310 p. : _bill. ; _c25 cm. |
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| 504 | _aIncludes bibliographical references and index. | ||
| 505 | 8 | _a(Publisher-supplied data) RNA interference: What is it? / James A. Birchler -- Nucleic acids as regulatory molecules / Faqing Huang, CJ Yu, and Yanlin Guo -- Use of siRNA oligonucleotides to study gene function / Kristin A. Wiederholt and Adam N. Harris -- Genome scanning by RNA interference / Roderick L. Beijersbergen and Oliver C. Steinbach -- Discovery of new siRNA delivery agents / Paul H. Johnson, Diane Frank, Kunyuan Cui, Roger Adami, Harry Wang, Michael Houston, and Steven C. Quay -- In vivo Delivery of siRNA: challenges and strategies / Aliasger K. Salem and Mark A. Behlke -- Interferon, cytokine induction and other potential in vivo toxicities / Adam Judge, Marjorie Robbins, and Ian MacLachlan -- Application of RNA interference to viral diseases / Ralph A. Tripp and Stephen Mark Tompkins. | |
| 520 | _a'RNA Interference: Application to Drug Discovery and Challenges to Pharmaceutical Development provides a general overview of this rapidly emerging field, with a strong emphasis on issues and aspects that are important to a drug development team. The first part covers more general background of RNA interference and its application in drug discovery. In the second part, the book addresses siRNA (small interfering RNA), a pharmaceutically potent form, and its use and delivery in therapeutics along with manufacturing and delivery aspects'--Provided by publisher. | ||
| 650 | 2 | _aRNA Interference. | |
| 650 | 2 | _aDrug Discovery. | |
| 700 | 1 |
_aJohnson, Paul H., _d1943- |
|
| 907 |
_a.b15327747 _b2021-05-28 _c2019-11-12 |
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| 942 |
_c01 _n0 _kQU475.R481 2011 9 |
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| 914 | _avtls003496900 | ||
| 991 | _aFakulti Farmasi, KKL | ||
| 998 |
_ad _b2012-03-04 _cm _da _feng _gnju _y0 _z.b15327747 |
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| 999 |
_c516605 _d516605 |
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