000 02582nam a2200373 a 4500
005 20250930133108.0
008 120316s2011 enkm b a001 0 eng
020 _a9781849731607 (hbk.)
_cRM654.71
020 _a1849731608 (hbk.)
039 9 _a201205161205
_bzabidah
_c201205161205
_dzabidah
_c201205161202
_dzabidah
_c201205161200
_dzabidah
_y03-16-2012
_zrasyilla
040 _dUKM
090 _aQP517.C45E978
090 _aQP517.C45
_bE978
245 0 0 _aExtracellular and intracellular signaling /
_cedited by James D. Adams Jr., Keith K. Parker.
260 _aCambridge, UK :
_bRSC Publishing,
_c2011.
300 _axiii, 303 p. :
_bill. (some col.) ;
_c24 cm.
490 1 _aRSC drug discovery series ;
_vno. 10.
504 _aIncludes bibliographical references and index.
520 _aA'Intracellular cell signaling is a well understood process. However, extracellular signals such as hormones, adipokines, cytokines and neurotransmitters are vital to the process and have been largely ignored in other works on signaling. They are causative agents in hypertension, diabetes, heart disease, arthritis and other diseases. Aimed at medical professionals and pharmaceutical specialists, this book integrates for the first time extracellular and intracellular signaling processes and offers a fresh perspective on new targets for drug development. With contributions from leading international authorities, it is the result of close cooperation between the authors of the various chapters. Readers are introduced to a new approach to disease causation by adipokines and toxic lipids. Heart disease, migraines, stroke, Alzheimer's disease, diabetes, cancer, and arthritis are approached from the perspective of toxic lifestyle and accumulation of toxic proteins and lipids. Evidence is presented that by alterations in toxic lifestyles you can reduce the incidence of such diseases. New therapeutic targets involving adipokines, ceramide and endocannabinoids are also discussed.'--Back cover.
650 0 _aCellular signal transduction.
650 0 _aCell interaction.
650 0 _aDrug development.
700 1 _aAdams, James D.,
_cJr.
_q(James David)
700 1 _aParker, Keith K.
_q(Keith Krom)
_958678
710 2 _aRoyal Society of Chemistry (Great Britain)
830 0 _aRSC drug discovery series ;
_v10.
907 _a.b15277756
_b2021-05-28
_c2019-11-12
942 _c01
_n0
_kQP517.C45E978
914 _avtls003491532
990 _aza
991 _aFakulti Sains dan Teknologi
998 _at
_b2012-03-03
_cm
_da
_feng
_genk
_y0
_z.b15277756
999 _c511689
_d511689