000 01862nam a22002898i 4500
005 20250918151248.0
008 120308s2011 flu b 001 0 eng
020 _a9781439810675
_cRM409.12
039 9 _a201205021144
_bzainol
_y03-08-2012
_zyusri
040 _aUKM
090 _aWN415.W714r 2011 9
090 _aWN415
_b.W714r 2011 9
100 1 _aWilliams, Lawrence E.
245 1 0 _aRadiopharmaceuticals :
_bintroduction to drug evaluation and dose estimation /
_cLawrence E. Williams.
260 _aBoca Raton :
_bCRC Press,
_c2011.
300 _axxi, 304 p. :
_bill. ;
_c24 cm.
520 _a'This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT /CT and PET/CT'--Provided by publisher.
650 2 _aRadiopharmaceuticals.
650 2 _aClinical Trials as Topic.
650 2 _aRadiopharmaceuticals
_xadministration & dosage.
907 _a.b15263496
_b2021-05-28
_c2019-11-12
942 _c01
_n0
_kWN415.W714r 2011 9
914 _avtls003489997
991 _aFakulti Farmasi, KKL.
998 _ad
_b2012-08-03
_cm
_da
_feng
_gflu
_y0
_z.b15263496
999 _c510411
_d510411