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020 _a9780781750097
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090 _aQV38.R883c 2011 9
090 _aQV38
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100 1 _aRowland, Malcolm.
245 1 0 _aClinical pharmacokinetics and pharmacodynamics :
_bconcepts and applications /
_cMalcolm Rowland and Thomas N. Tozer.
250 _a4th ed.
260 _aPhiladelphia :
_bLippincott William & Wilkins,
_cc2011.
300 _axxii, 839 p. :
_bill. ;
_c26 cm.
500 _aThis book includes online access at http://thepoint.lww.com/Rowland4e, please refer to library staff for the password.
505 0 _aTherapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data.
650 2 _aPharmacokinetics.
650 2 _aDrug Therapy.
700 1 _aTozer, Thomas N.
700 1 _aRowland, Malcolm.
_tClinical pharmacokinetics.
907 _a.b15223747
_b2021-05-28
_c2019-11-12
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990 _awafi/sue
991 _aJabatan Farmasi, KKL
991 _aJabatan Farmakologi, Pra Klinikal PPUKM
998 _a(2)d
_ap
_b2012-04-01
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