000 02176nam a22003618a 4500
005 20250918140545.0
008 110426s2011 njua b 001 0 eng
020 _a9780470504789 (hbk.)
_cRM312.90
039 9 _a201106281641
_brosli
_c201106151516
_drahah
_c201104261538
_drahah
_y04-26-2011
_zrahah
040 _aUKM
090 _aQP529.B536
090 _aQP529
_b.B536
245 0 0 _aBiotransformation and metabolite elucidation of xenobiotics /
_cedited by Ala F. Nassar.
260 _aHoboken, N.J. :
_bJohn Wiley & Sons,
_cc2011.
300 _axi, 328 p. :
_bill. ;
_c25 cm.
504 _aIncludes bibliographical references and index.
505 0 _aHuman biotransformation / Andrew Parkinson -- Analytical tools and approaches for metabolite identification in drug metabolism / Yongmei Li -- Tools of choice for accelerating metabolite identification : mass spec technology drives metabolite identification studies forward / Ala Nassar -- Improving drug design : considerations for the structural modification process / Ala Nassar -- Case study : the unanticipated loss of N2 from novel dna alkylating agent laromustine by collision-induced dissociation : novel rearrangements / Ala Nassar, Tukiet T. Lam -- Case study : identification of in vitro metabolite/decomposition products of the novel DNA alkylating agent laromustine / Ala Nassar, TuKiet T. Lam -- Strategies for the detection of reactive intermediates in drug discovery and development / Mark P. Grillo -- Safety testing of drug metabolites : MIST guidance impact on the practice of industrial drug metabolism / J. Greg Slatter.
650 0 _aXenobiotics
_xMetabolism.
650 0 _aMetabolites
_xIdentification.
650 0 _aBiotransformation (Metabolism)
650 1 2 _aXenobiotics
_xmetabolism.
650 1 2 _aXenobiotics
_xpharmacology.
650 2 2 _aBiotransformation
_xphysiology.
650 2 2 _aDrug Discovery.
700 1 _aNassar, Ala F.
907 _a.b15019858
_b2021-05-28
_c2019-11-12
942 _c01
_n0
_kQP529.B536
914 _avtls003464237
990 _ark4
991 _aFakulti Sains & Teknologi
998 _at
_b2011-01-04
_cm
_da
_feng
_gnju
_y0
_z.b15019858
999 _c486704
_d486704