| 000 | 04909nam a2200421 a 4500 | ||
|---|---|---|---|
| 005 | 20250914160559.0 | ||
| 008 | 070515s2006 xxua 001 0 eng | ||
| 020 |
_a0849327792 (alk. paper) _cRM671.24 |
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| 020 | _a9780849327797 | ||
| 039 | 9 |
_a200707241337 _bwmeriam _c200705231200 _dzainol _y05-15-2007 _zrazalis |
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| 060 |
_aQV744 _b.P964 2006 9 |
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| 090 | _aQV744.P964 2006 9 | ||
| 245 | 0 | 4 |
_aThe process of new drug discovery and development / _cedited by Charles G. Smith, James T. O'Donnell |
| 250 | _a2nd ed. | ||
| 260 |
_aNew York : _bInforma Healthcare, _c2006 |
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| 300 |
_a668 p. : _bill. ; _c27 cm. |
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| 500 | _aRev. ed. of: The process of new drug discovery and development / Charles G. Smith. 1992 | ||
| 505 | 0 | _aOverview of the current process of new drug discovery and development / Charles G. Smith and James T. O'Donnell -- Integrated drug product development: from lead candidate selection to life-cycle management / Madhu Pudipeddi, Abu T.M. Serajuddin, and Daniel Mufson -- The impact of combinatorial chemistry on drug discovery / Michael H. Rabinowitz and Nigel Shankley -- High-throughput screening: enabling and influencing the process of drug discovery / Carol Ann Homon and Richard M. Nelson -- Pharmacological and pharmaceutical profiling: new trends / Joanne Bowes ... [et al.] -- Cell-based analysis of drug response using moving optical gradient fields / Jeff M. Hall ... [et al.] | |
| 505 | 0 | _aPatient-derived primary cells in high-throughput differential antitumor screens: let the patients be the guide / Irwin A. Braude -- The evolving role of the caco-2 cell model to estimate intestinal absorption potential and elucidate transport mechanisms / Jibin Li and Ismael J. Hidalgo -- | |
| 505 | 0 | _aThe promise of metabonomics in drug discovery / Harold J. Kwalwasser and Pauline Gee -- Pharmacogenetics and pharmacogenomics in drug development and regulatory decision-making: report of the first FDA-PWG-PhRMA-druSafe workshop / Lawrence J. Lesko ... [et al.] -- Drugs from molecular targets for CNS and neurodegenerative diseases / William T. Comer and G诮赬 Veli{u396C}ebi -- Safety pharmacology / Jean-Pierre Valentin and Tim G. Hammond -- Nonclinical drug safety assessment / Frederick E. Reno -- Preclinical genotoxicity testing: past, present and future / Richard H.C. San -- The need for animals in biomedical research / Charles G. Smith -- Defining the actual research approach to the new drug substance / Charles G. Smith -- Pharmacokinetics: pharmacodynamics in new drug development / Sarfaraz K. Niazi -- | |
| 505 | 0 | _aPharmaceutics and compounding issues in new drug development and marketing / Loyd V. Allen -- Late stage and process development activities / Charles G. Smith -- Contract research organizations: role and function in new drug development / F. Richard Nichol -- The front lines of clinical research: the industry / Lori Nesbitt -- Horizons for cancer chemotherapy (and nonchemotherapy) / Daniel D. Von Hoff -- Human immunodeficiency virus/acquired immune deficiency syndrome: clinical testing challenges / Vincent Idemyor -- Common technical document: the changing face of the new drug application / Justina A. Molzon -- Electronic publishing / Heather L. Wallace -- The important role of pharmacists in a complex risk-management system: managing the risks from medical product use by focusing on patient education, monitoring, and adverse event reporting / Justina A. Molzon -- Liability, litigation, and lessons in new drug development / James T. O'Donnell -- Problems in the nondrug marketplace / Stephen Barrett -- Patents and new product development in the pharmaceutical and biotechnology industries / Henry Grabowski -- | |
| 505 | 0 | _aThe pharmaceutical revolution: drug discovery and development / John C. Somberg -- The discovery of Rituxan / Mitchell E. Reff -- Funding the birth of a drug: lessons from the sell side / Howard E. Greene -- Innovations for the drug development pathway: what is needed now / Janet Woodcock -- Managing R & D uncertainty and maximizing the commercial potential of pharmaceutical compounds using the dynamic modeling framework / Mark Paich ... [et al.]. | |
| 650 | 2 | _aDrug Design | |
| 650 | 2 | _aDrug Evaluation, Preclinical | |
| 650 | 2 | _aDrug evaluation | |
| 700 | 1 |
_aSmith, Charles G. _q(Charles Giles) |
|
| 700 | 1 |
_aO'Donnell, James, _cPharm. D. |
|
| 700 | 1 |
_aSmith, Charles G. _q(Charles Giles) _tProcess of new drug discovery and development |
|
| 856 | 4 | 1 |
_3Table of contents _uhttp://www.loc.gov/catdir/toc/ecip065/2005036791.html |
| 856 | 4 | 2 |
_3Publisher description _uhttp://www.loc.gov/catdir/enhancements/fy0647/2005036791-d.html |
| 907 |
_a.b13919362 _b2019-11-12 _c2019-11-12 |
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| 942 |
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| 990 | _azr | ||
| 991 | _aJabatan Farmasi | ||
| 998 |
_ad _b2007-02-05 _cm _da _feng _gxxu _y0 _z.b13919362 |
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