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_cRM220.68
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_bsue
_c200504071458
_dnor
_y03-30-2005
_zbalqis
060 _aQV39
090 _aQV39.R612h 2004
100 1 _aRitschel, Wolfgang A.
245 1 0 _aHandbook of basic pharmacokinetics ... including clinical applications /
_cWolfgang A. Ritschel, Gregory L. Kearns
250 _a6th ed.
260 _aWashington :
_bAmerican Pharmacists Association,
_c2004
300 _axii, 431 p. :
_bill. ;
_c26 cm.
505 0 _aDefinitions and glossary -- The LADMER system: liberation, absorption, distribution, metabolism, elimination, and response -- Organs, tissues, cells, and organelles -- Cell membranes -- Drug-receptor interactions -- Absorption/transport mechanisms -- pKa and degree of ionization -- Lipid/water partition coefficient -- Physicochemical factors altering biological performance of drugs -- Biopharmaceutical data of the gastrointestinal tract -- Fluid compartments and circulatory system -- Binding of drugs to biological material -- Drug biotransformation -- Compartment models -- Determination of rate constants -- Volume of distribution and distribution coefficient -- Excretion and clearance of drugs -- Urinary and biliary recycling --
505 0 _aCumulative urinary excretion -- Area under the blood level-time curve -- Pharmacokinetics of single dose administration -- Pharmacokinetics of multiple dosing -- Compartment model independent analysis -- Pediatric pharmacokinetics -- Drug dosage in elderly patients -- Drug dosage in obese patients -- Drug disposition in pregnancy -- Dosage regimen design -- Drug monitoring and dosage adjustment -- Physiological and pathological factors influencing drug response -- First dose size in man -- Forensic pharmacokinetics -- Nonlinear pharmacokinetics -- Curve fitting -- Correlation of clinical response with drug disposition -- Bioavailability and bioequivalence -- Body surface areas -- Extracorporeal methods of drug removal -- Pharmacogenetics and pharmacogenomics
650 2 _aPharmacokinetics
_vHandbooks
700 1 _aKearns, Gregory L.
710 2 _aAmerican Pharmaceutical Association
907 _a.b13502037
_b2019-11-12
_c2019-11-12
942 _c01
_n0
_kQV39.R612h 2004
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990 _anorhayati
991 _aJabatan Farmasi, HUKM
998 _ah
_b2005-04-03
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