000			02292nam a2200349 a 4500
005			20250914133936.0
008			040601s2004 gx a b 001 0 eng
020			_a3527304312 (alk. paper) _cRM703.50
039		9	_a200510271233 _bnor _c200410211238 _dlailawati _c200408231447 _drapiza _y06-01-2004 _zfaizah
060			_aQV744
090			_aQV744.M718 2004
245	0	0	_aMolecular biology in medicinal chemistry / _cedited by Th. Dingermann, D. Steinhilber, and G. Folkers
260			_aWeinheim : _bWiley-VCH, _c2004
300			_axxi, 413 p. : _bill. ; _c24 cm.
440		0	_aMethods and principles in medicinal chemistry ; _vv. 21
505	0		_aCellular assays in drug discovery -- Gene knockout models -- Reporter gene assay systems for the investigation of GPCRs -- From the human genome to new drugs: The potential of orphan GPCRs -- Stereoselective synthesis with the help of recombinant enzymes -- Nucleic acid drugs -- Recent trends in enantioseparation of chiral drugs -- Affinity chromatography -- NMR-based drug discovery -- 13C- and 15N-Isotopic labeling of proteins -- Antibody fragments as crystallization enhancers -- Pharmacogenetics: the effect of inherited henetic variation on drug disposition and drug response -- Pharmacogenomics of bioavailability and elimination -- Toxicogenomics: integration of new molecular biological tools in toxicology
520			_aExplains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. Appropriate for pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action
650		2	_aChemistry, Pharmaceutical
650		2	_aGenetic engineering
650		2	_aMolecular biology
700	1		_aDingermann, Theodor
700	1		_aSteinhilber, Dieter, _d1959-
700	1		_aFolkers, Gerd.
907			_a.b13387352 _b2019-11-12 _c2019-11-12
942			_c01 _n0 _kQV744.M718 2004
914			_avtls003290426
990			_azaa
991			_aJabatan Farmasi, KKL
991			_aJabatan Farmasi, HUKM
998			_ad _ah _b2004-01-06 _cm _da _feng _g _y0 _z.b13387352
999			_c338063 _d338063