TY  - BOOK
AU  - Clark,David E.
ED  - Wiley InterScience (Online service)
TI  - Evolutionary algorithms in molecular design
T2  - Methods and principles in medicinal chemistry
SN  - 9783527613168
AV  - QA402.5 .E956 2000eb
U1  - 541.220285631 22
PY  - 2000///
CY  - Weinheim, New York
PB  - Wiley-VCH
KW  - Genetic algorithms
KW  - Drugs
KW  - Design and construction
KW  - Molecules
KW  - Models
KW  - Evolutionary programming (computer science)
KW  - Drug Design
KW  - Algorithms
KW  - Computer-aided design
KW  - Evolution, Molecular
KW  - Geometric algorithms
KW  - SCIENCE
KW  - Chemistry
KW  - Physical & Theoretical
KW  - bisacsh
KW  - Electronic books
N1  - Includes bibliographical references and index; Evolutionary Algorithms in Molecular Design; Contents; 1 Introduction to Evolutionary Algorithms; 2 Small-molecule Geometry Optimization and Conformational Search; 3 Protein-Ligand Docking; 4 De Now Molecular Design; 5 Quantitative Structure- Activity Relationships; 6 Chemometrics; 7 Chemical Structure Handling; 8 Molecular Diversity Analysis and Combmatorial Library Design; 9 Evolutionary Algorithms in Crystallographic Applications; 10 Structure Determination by NMR Spectroscopy; 11 Protein Folding; 12 New Techniques and Future Directions
N2  - When trying to find new methods and problem-solving strategies for their research, scientists often turn to nature for inspiration. An excellent example of this is the application of Darwin's Theory of Evolution, particularly the notion of the'survival of the fittest', in computer programs designed to search for optimal solutions to many kinds of problems. These'evolutionary algorithms' start from a population of possible solutions to a given problem and, by applying evolutionary principles, evolve successive generations with improved characteristics until an optimal, or near-optimal, soluti
UR  - https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://onlinelibrary.wiley.com/book/10.1002/9783527613168
ER  -