Evolutionary algorithms in molecular design / 
edited by David E. Clark. 
 - Weinheim ;  New York :  Wiley-VCH,  ©2000. 
 - 1 online resource (280 pages) :  illustrations. 
 - Methods and principles in medicinal chemistry ;  v. 8 .
 - Methods and principles in medicinal chemistry ;  v. 8. .
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Evolutionary Algorithms in Molecular Design; Contents; 1 Introduction to Evolutionary Algorithms; 2 Small-molecule Geometry Optimization and Conformational Search; 3 Protein-Ligand Docking; 4 De Now Molecular Design; 5 Quantitative Structure- Activity Relationships; 6 Chemometrics; 7 Chemical Structure Handling; 8 Molecular Diversity Analysis and Combmatorial Library Design; 9 Evolutionary Algorithms in Crystallographic Applications; 10 Structure Determination by NMR Spectroscopy; 11 Protein Folding; 12 New Techniques and Future Directions. 
<br/><br/> When trying to find new methods and problem-solving strategies for their research, scientists often turn to nature for inspiration. An excellent example of this is the application of Darwin's Theory of Evolution, particularly the notion of the'survival of the fittest', in computer programs designed to search for optimal solutions to many kinds of problems. These'evolutionary algorithms' start from a population of possible solutions to a given problem and, by applying evolutionary principles, evolve successive generations with improved characteristics until an optimal, or near-optimal, soluti. 
<br/><br/><label>ISBN: </label>9783527613168 3527613161 9783527613175 352761317X 
<br/><br/><label>Standard No.: </label>10.1002/9783527613168  doi 
<br/><br/><label>Source: </label>10.1002/9783527613168  Wiley InterScience  http://www3.interscience.wiley.com 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Genetic algorithms.<br/>Drugs--Design and construction.<br/>Molecules--Models--Design and construction.<br/>Evolutionary programming (computer science)<br/>Drug Design.<br/>Algorithms.<br/>Computer-aided design.<br/>Evolution, Molecular.<br/>Geometric algorithms.<br/>SCIENCE--Chemistry--Physical & Theoretical.
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>QA402.5  / .E956 2000eb 
<br/><br/><label>Dewey Class. No.: </label>541.220285631 
<br/><br/><label>National Library of Medicine Call No.: </label>W1  / ME9613H v.8 2000 QV 744  / E94 2000