TY  - BOOK
AU  - Markowetz,Florian
AU  - Boutros,Michael
TI  - Systems Genetics: Linking Genotypes and Phenotypes 
T2  - Cambridge Series in Systems Genetics
SN  - 9781139012751 (ebook)
AV  - QH438.5 .S97 2015
U1  - 576.5 23
PY  - 2015///
CY  - Cambridge
PB  - Cambridge University Press
KW  - Phenotype
KW  - Genetics
KW  - Functional genomics
N1  - Title from publisher's bibliographic system (viewed on 07 Mar 2017)
N2  - Whereas genetic studies have traditionally focused on explaining heritance of single traits and their phenotypes, recent technological advances have made it possible to comprehensively dissect the genetic architecture of complex traits and quantify how genes interact to shape phenotypes. This exciting new area has been termed systems genetics and is born out of a synthesis of multiple fields, integrating a range of approaches and exploiting our increased ability to obtain quantitative and detailed measurements on a broad spectrum of phenotypes. Gathering the contributions of leading scientists, both computational and experimental, this book shows how experimental perturbations can help us to understand the link between genotype and phenotype. A snapshot of current research activity and state-of-the-art approaches to systems genetics are provided, including work from model organisms such as Saccharomyces cerevisiae and Drosophila melanogaster, as well as from human studies
UR  - https://eresourcesptsl.ukm.remotexs.co/user/login?url=https://doi.org/10.1017/CBO9781139012751
ER  -