Chagas disease /
edited by Louis M. Weiss, Herbert B. Tanowitz and Louis V. Kirchhoff.
- Amsterdam : Academic, 2011.
- 1 online resource (2 volumes) : illustrations (some color), maps (some color).
- Advances in parasitology, v. 75-76 0065-308X ; .
- Advances in parasitology ; v. 75-76. .
Epidemiology of american trypanosomiasis (Chagas disease) / Acute and congeital Chagas disease / Caryn Bern, Diana L. Martin, and Robert H. Gilman -- Cell-based therapy in Chagas disease / Targeting trypanosoma cruzi sterol 14[alpha]-Demethylase (CYP51) / Experimental chemotherapy and approaches to drug discovery for trypanosoma cruzi infection / Vaccine development against trypanosoma cruzi and Chagas disease / Genetic epidemiology of Chagas disease / Kissing bugs. The vectors of Chagas / Advances in imaging of animal models of Chagas disease / The genome and its implications / Genetic techniques in trypanosoma cruzi / Nuclear structure of trypanosoma cruzi / Aspects of trypanosoma cruzi stage differentiation / The role of acidocalcisomes in the stress response of trypanosoma cruzi / Signal transduction in trypanosoma cruzi / t Louis V. Kirchhoff -- Antonio C. Campos de Carvalho, Adriana B. Carvalho, and Regina C.S. Goldenberg -- Galina I. Lepesheva, Fernando Villalta, and Michael R. Waterman -- Frederick S. Buckner -- Juan C. Vquez-Chagoy, Shivali Gupta, and Nisha Jain Garg -- Sarah Williams-Blangero, John L. VandeBerg, John Blangero, and Rodrigo Corr-Oliveira -- Lori Stevens [and others] -- Linda A. Jelicks and Herbert B. Tanowitz -- Santuza M. Teixeira, Najib M. El-Sayed, and Patria R. Arao -- Martin C. Taylor, Huan Huang, and John M. Kelly -- Sergio Schenkman, Bruno dos Santos Pascoalino, and Sheila C. Nardelli -- Samuel Goldenberg and Andrea Rodrigues ⁶ila -- Roberto Docampo [and others] -- Huan Huang. pt. A. Bioactive lipids in trypanosome cruzi infection / Mechanisms of host cell invasion by trypanosome cruzi / Gap junctions and Chagas disease / The vasculature in Chagas disease / Infection-associated vasculopathy in experimental Chagas disease: pathogenic roles of endothelin and kinin pathways / Autoimmunity / ROS signaling of inflammatory cytokines during trypanosome cruzi infection / Inflammation and Chagas disease: some mechanisms and relevance / Neurodegeneration and neuroregeneration in Chagas disease / Adipose tissue, diabetes and Chagas disease / Fabiana S. Machado, et al -- Kacey L. Caradonna and Barbara A. Burleigh -- Daniel Adesse, et al -- Cibele M. Prado, et al -- Julio Scharfstein and Daniele Andrade -- Edecio Cunha-Neto, et al -- Shivali Gupta, et al -- Andre Talvani and Mauro M. Teixeira -- Marina V. Chuenkova and Mercio PereiraPerrin -- Herbert B. Tanowitz, et al. pt. B.
This thematic volume provides authoritative, up-to-date reviews addressing recent advances as well as an overview for the research and clinical communities on the endemic infection of Chagas disease. Lead researchers discuss epidemiology and control measures as well as various diagnosis techniques, treatments, and therapies currently being used. The text includes a history of Chagas disease and an outlook for the next century. Informs and updates on all the latest developments in the field Contributions from leading authorities and industry experts.