Statistical methods in drug combination studies / edited by Wei Zhao, Harry Yang. - xvi, 224 pages : illustrations ; 25 cm. - Chapman & Hall/CRC biostatistics series . - Chapman & Hall/CRC biostatistics series. .

'A Chapman & Hall book.'

Includes bibliographical references and index.

Drug combination : much promise and many hurdles / Harry Yang and Laura Richman -- Drug combination synergy / Harry Yang, Steven J. Novick, and Wei Zhao -- Drug combination design strategies / Steven J. Novick and John J. Peterson -- Confidence interval for interaction index / Maiying Kong and J. Jack Lee -- Two-stage response surface approaches to modeling drug interaction / Wei Zhao and Harry Yang -- A bayesian industry approach to phase I combination trials in oncology / Beat Neuenschwander, Alessandro Matano, Zhongwen Tang, Satrajit Roychoudhury, Simon Wandel, Stuart Bailey -- Statistical methodology for evaluation combination therapy in clinical trials / H.M. James Hung, Sue-Jane Wang -- Challenges and opportunities in analysis of drug combination clinical trial data / Yaning Wang, Hao Zhu, Liang Zhao, and Ping Ji -- Statistical computational tools for ADA analysis / Cheng Su.

9781482216745 (hardcover : acid-free paper) RM449.54


Drug combinations.
Clinical Trials as Topic.
Drug Design.
Drug Therapy, Combination.
Models, Statistical.