Pharmacogenomics in drug discovery and development / edited by Qing Yan, PharmTao, Santa Clara, CA, USA. - Second edition. - xiii, 715 pages : illustrations (some colour, chiefly tables) ; 26 cm. - Methods in molecular biology, 1175 1064-3745 ; Springer protocols . - Methods in molecular biology (Clifton, N.J.) ; 1175. Springer protocols (Series) .

Includes bibliographical references and index.

From pharmacogenomics and systems biology to personalized care : a framework of systems and dynamical medicine / Translational bioinformatics approaches for systems and dynamical medicine / Whole blood transcriptomic analysis to identify clinical biomarkers of drug response / Diagnostic procedures for paraffin-embedded tissues analysis in pharmacogenomic studies / Approach to clinical and genetic characterization of statin-induced myopathy / Pharmacogenomics of membrane transporters : a review of current approaches / G protein-coupled receptor accessory proteins and signaling : pharmacogenomic insights / G protein-coupled receptor mutations and human genetic disease / Pharmacogenetics of the G protein-coupled receptors / Pharmacogenomics of heart failure / Pharmacogenomics in the development and characterization of atheroprotective drugs / Management of side effects in the personalized medicine era : chemotherapy-induced peripheral neuropathy / Pharmacogenomics of Alzheimer's disease : novel therapeutic strategies for drug development / Pharmacogenetics of antipsychotic treatment in schizophrenia / Pharmacogenetics of addiction therapy / Pharmacogenetics in rheumatoid arthritis / Pharmacogenetics of osteoporotic fractures / Pharmacogenomics and pharmacoepigenomics in pediatric medicine / Pharmacogenomics in children / Qing Yan -- Qing Yan -- Grant P. Parnell and David R. Booth -- Raffaele Palmirotta [and six others] -- QiPing Feng -- Tristan M. Sissung [and four others] -- Miles D. Thompson [and three others] -- Miles D. Thompson [and four others] -- Miles D. Thompson [and six others] -- Anastasios Lymperopoulos and Faren French -- Efi Valanti, Alexandros Tsompanidis, and Despina Sanoudou -- Paolo Alberti and G. Cavaletti -- Ram Cacabelos [and four others] -- Jennie G. Pouget and Daniel J. M赬ler / David A. Nielsen [and three others] -- Deepali Sen, Jisna R. Paul, and Prabha Ranganathan -- JosA. Riancho and Flor M. Pez-Campo -- Barkur S. Shastry -- Michael Rieder.

9781493909551 (hbk : acid-free paper) RM694.51 149390955X (hbk : acid-free paper)


Pharmacogenetics--methods.
Biotransformation--genetics.
Drug Design.
Pharmacokinetics.