Ocular Drug Delivery Systems : Barriers and Application of Nanoparticulate Systems /
edited by Deepak Thassu and Gerald J. Chader.
- xv, 447 pages, [10] pages of plates : illustrations (some color) ; 24 cm.
Includes bibliographical references and index.
Nanoparticulate-based therapeutics: an overview / Eye anatomy, physiology and ocular barriers: basic considerations for drug delivery / Animal models to evaluate nanoparticulate drug delivery systems / Computer modeling for ocular drug delivery / Considerations for development of ophthalmic nanotechnology-based drugs / Blood-retinal barrier: the fundamentals / Barriers to transscleral drug delivery to the retina / Drug delivery to the vitreous humor / Transscleral and suprachoroidal drug delivery / Protein drug delivery to retina and choroid / Transscleral drug delivery to the posterior segment of the eye / Drug delivery to the suprachoroidal space / Use of nanoparticles in the treatment of age-related macular degeneration, glaucoma and other degenerative retinal diseases / Drug molecule characteristics and their impact on anterior versus posterior segment drug delivery strategies / Surface modulation of nanoparticles / Nanoparticles for the treatment of retinal diseases / Amin Famili and Uday B. Kompella -- Gene-based medicine for ocular diseases / Stealth-type polymeric nanoparticles with encapsulated betamethasone phosphate for treatment of intraocular inflammation / Nanotechnology-guided imaging of retinal vascular disease / Photoresponsive polymers for ocular drug delivery / Nanosuspensions in ocular drug delivery systems / Deepak Thassu, Kris Holt, and Gerald J. Chader -- Gerald J. Chader and Deepak Thassu -- Vinson M. Wang, Jingsheng Tuo, and Chi-Chao Chan -- Paul J. Missel -- Banu S. Zolnik, Sherizaq Baksh, and Nakissa Sadrieh -- Rosa Fernandes, Andreia Gonves, and JosCunha-Vaz -- Alexandra Almazan ... [et al.] -- Francine Behar-Cohen -- Damian E. Berezovsky and Henry Edelhauser -- Hogwen M. Rivers and Patrick M. Hughes -- Bernard F. Godley ... [et al.] -- Sung Won Cho and Timothy Olsen -- Marco A. Zarbin ... [et al.] -- Kay D. Rittenhouse -- Deepak Thassu and Kris Holt -- Shannon M. Conley and Muna I. Naash -- Tsutomu Sakai, Tsutomu Ishihara, and Megumu Higaki -- Joshua R. Trantum, John S. Penn, and Ashwath Jayagopal -- Laura A. Wells and Heather Sheardown -- Himanshu Bhattacharjee and Sonia Bedi. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. t21.