Systems metabolic engineering :  methods and protocols / 
edited by Hal S. Alper. 
 - New York :  Humana Press,  2013. 
 - xii, 474 p. :  ill. ;  cm. 
 - Methods in molecular biology ;  v. 985 .
 - Methods in molecular biology .
<br/><br/>Includes bibliographical references and index. 
<br/><br/> Genome-scale model management and comparison /  Automated genome annotation and metabolic model reconstruction in the SEED and model SEED /  Metabolic model refinement using phenotypic microarray data /  Linking genome-scale metabolic modeling and genome annotation /  Resolving cell composition through simple measurements, genome-scale modeling, and a genetic algorithm /  Guide to integrating transcriptional regulatory and metabolic networks using PROM (probabilistic regulation of metabolism) /  Kinetic modeling of metabolic pathways : application to serine biosynthesis /  Computational tools for guided discovery and engineering of metabolic pathways /  Retrosynthetic design of heterologous pathways /  Customized optimization of metabolic pathways by combinatorial transcriptional engineering /  Adaptive laboratory evolution for strain engineering /  Trackable multiplex recombineering for gene-trait mapping in E. coli /  Identification of mutations in evolved bacterial genomes /  Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies /  13C-based metabolic flux analysis : fundamentals and practice /  Nuclear magnetic resonance methods for metabolic fluxomics /  Using multiple tracers for 13C metabolic flux analysis /  Isotopically nonstationary 13C metabolic flux analysis /  Sample preparation and biostatistics for integrated genomics approaches /  Targeted metabolic engineering guided by computational analysis of single-nucleotide polymorphisms (SNPs) /  Linking RNA measurements and proteomics with genome-scale models /  Comparative transcriptome analysis for metabolic engineering /  Merging multiple omics datasets in silico : statistical analyses and data interpretation /  Stephan Pabinger and Zlatko Trajanoski --  Scott Devoid ... [et al.] --  Pratish Gawand ... [et al.] --  Edik M. Blais, Arvind K. Chavali, and Jason A. Papin --  Ryan S. Senger and Hadi Nazem-Bokaee --  Evangelos Simeonidis, Sriram Chandrasekaran, and Nathan D. Price --  Kieran Smallbone and Natalie J. Stanford --  Matthew Moura, Linda Broadbelt, and Keith Tyo --  Pablo Carbonell, Anne-Gaelle Planson, and Jean-Loup Faulon --  Yongbo Yuan, Jing Du, and Huimin Zhao --  James Winkler, Luis H. Reyes, and Katy C. Kao --  Thomas J. Mansell, Joseph R. Warner, and Ryan T. Gill --  Liam Royce ... [et al.] --  Grant Gelderman and Lydia M. Contreras --  Tae Hoon Yang --  Shilpa Nargund ... [et al.] --  Maciek R. Antoniewicz --  Lara J. Jazmin and Jamey D. Young --  Hein Stam ... [et al.] --  D.B.R.K. Gupta Udatha ... [et al.] --  Christopher M. Gowen and Stephen S. Fong --  Shuobo Shi, Tao Chen, and Xueming Zhao --  Kazuharu Arakawa and Masaru Tomita. 
<br/><br/><label>ISBN: </label>9781627032988 (hbk.)  RM452.28 1627032983 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Metabolism.<br/>Biomedical engineering.<br/>Systems Biology.