TY - BOOK AU - Wong,Shan S. AU - Jameson,David M. AU - Wong,Shan S. TI - Chemistry of protein and nucleic acid cross-linking and conjugation SN - 9780849374913 (hbr) PY - 2012/// CY - Boca Raton PB - CRC Press KW - Proteins KW - Crosslinking KW - chemistry KW - Cross-Linking Reagents KW - Immunoconjugates KW - therapeutic use KW - Nucleic Acids N1 - Rev. ed. of: Chemistry of protein conjugation and cross-linking. c1991; Includes bibliographical references and index; Overview of protein conjugation -- Review of protein and nucleic acid chemistry -- Reagents targeted to specific functional groups -- How to design and choose cross-linking reagents -- Homobifunctional cross-linking reagents -- Heterobifunctional cross-linkers -- Multifunctional cross-linking reagents -- Monofunctional and zero-length cross-linking reagents -- General approaches for chemical cross-linking -- Analysis of cross-linked products -- Applications of chemical cross-linking to the study of biological macromolecules -- Applications of chemical conjugation in the preparation of immunoconjugates and immunogens -- Application of chemical conjugation for the preparation of immunotoxins and other drug conjugates for targeting theraputics ER -