Rowland, Malcolm. <br/><br/>
Clinical pharmacokinetics and pharmacodynamics :  concepts and applications / 
Malcolm Rowland and Thomas N. Tozer. 
 - 4th ed. 
 - Philadelphia :  Lippincott William & Wilkins,  c2011. 
 - xxii, 839 p. :  ill. ;  26 cm. 
<br/><br/> This book includes online access at http://thepoint.lww.com/Rowland4e, please refer to library staff for the  password. 
<br/><br/>Therapeutic relevance -- Fundamental concepts and terminology -- Kinetics following an intravenous bolus dose -- Membranes and distribution -- Elimination -- Kinetics following an extravascular dose -- Absorption -- Response following a single dose -- Therapeutic window -- Constant-rate input -- Multiple dose regimens -- Variability -- Genetics -- Age, weight, and gender -- Disease -- Nonlinearities -- Drug interactions -- Initiating and managing therapy -- Distribution kinetics -- Metabolites and drug response -- Protein drugs -- Prediction and refinement of human kinetics from in vitro, preclinical, and early clinical data. 
<br/><br/><label>ISBN: </label>9780781750097  RM240.91 (PDAL) 9780781750097  RM269.41 (PPUKMPRA) 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Pharmacokinetics.<br/>Drug Therapy.