TY - BOOK AU - Stern,Robert TI - Hyaluronan in cancer biology SN - 9780123741783 PY - 2009/// CY - San Diego, CA PB - Academic Press KW - Hyaluronic acid KW - Pathophysiology KW - Carcinogenesis KW - Hyaluronic Acid KW - metabolism KW - Neoplasms KW - Metabolism KW - Antigens, CD44 KW - Disease Progression KW - therapeutic use N1 - Includes bibliographical references and index; Association between'acid mucopolysaccharides' and malignancy : an old concept comes of age, finally / Robert stern -- Hyaluronan : a constitutive regulator of chemoresistance and malignancy in cancer cells / Mark G. Slomiany and Bryan P. Toole -- Growth factor regulation of hyaluronan deposition in malignancies / Paraskevi Heldin, Eugenia Karousou, and Spyros S. Skandalis -- Hyaluronan binding protein 1 (HABP1) in cancer biology / Kasturi Datta -- CD44 meets merlin and ezrin : their interplay mediates the pro-tumor activity of CD44 and tumor-suppressing effect of merlin / Ivan Stamenkovic and Qin Yu -- Hyaluronan-mediated CD44 interaction with receptor and non-receptor kinases promotes oncogenic signaling, cytoskeleton activation, and tumor progression / Lilly Y.W. Bourguignon -- Adhesion and penetration : two sides of CD44 signal transduction cascades in the context of cancer cell metastasis / David J.J. Waugh ... [et al.] -- Involvement of CD44, a molecule with a thousand faces, in cancer dissemination / David Naor ... [et al.] -- Rhamm/Hmmr : an itinerant and multifunctional hyaluronan binding protein that modifies CD44 signaling and mitotic spindle formation / James B. McCarthy and Eva A. Turley -- Altered hyaluronan biosynthesis in cancer progression / Naoki Itano and Koji Kimata --; Hyaluronidase : both a tumor promoter and suppressor / Vinata B. Lokeshwar and Marie G. Selzer -- The hyaluronidases in cancer biology / Robert Stern -- Hyaluronan fragments : informational polymers commandeered by cancers / Kazuki N. Sugahara -- Hyaluronan in human tumors : importance of stromal and cancer cell-associated hyaluronan / Raija H. Tammi ... [et al.] -- The oncofetal paradigm revisited : MSF and HA as contextual drivers of cancer progression / Seth L. Schor ... [et al.] -- Hyaluronan synthesis and turnover in prostate cancer / Melanie A. Simpson -- Role of hyaluronan in melanoma progression / Carl Gebhardt ... [et al.] -- Role of hyaluronan metabolism in the initiation, invasion, and metastasis of breast cancer / Tracey J. Brown and Natalie Thomas -- Clinical application of hyaluronidase in combination cancer chemotherapy : a historic perspective / Gerhard Baumgartner and Gerhard Hamilton -- Exploring the hyaluronan:CD44 interaction for cancer therapy / Virginia M. Platt and Francis C. Szoka -- Hyaluronidase-2 and its role as a cell-entry receptor for sheep retroviruses that cause contagious respiratory tract cancers / A. Dusty Miller ER -