TY - BOOK AU - Wagner,Edward K. AU - Wagner,Edward K. TI - Basic virology SN - 9781405147156 (pbk. : alk. paper) PY - 2008/// CY - Malden, MA PB - Blackwell Pub. KW - Virus Diseases KW - virology KW - Genome, Viral KW - Virus Replication KW - Viruses KW - pathogenicity N1 - Includes bibliographical references (p. [499]-505) and index; Introduction: the impact of viruses on our view of life -- An outline of virus replication and viral pathogenesis -- Virus disease in populations and individual animals -- Patterns of some viral diseases of humans -- Virus structure and classification -- The beginning and end of the virus replication cycle -- Host immune response to viral infection: the nature of the vertebrate immune response -- Strategies to protect against and combat viral infection -- Visualization and enumeration of virus particles -- Replicating and measuring biological activity of viruses -- Physical and chemical manipulation of the structural components of viruses -- Characterization of viral products expressed in the infected cell -- Viruses use cellular processes to express their genetic information -- Replication of positive-sense RNA viruses -- Replication strategies of RNA viruses requiring RNA-directed mRNA transcription as the first step in viral gene expression -- Replication strategies of small and medium-sized DNA viruses -- Replication of some nuclear-replicating eukaryotic DNA viruses with large genomes -- Replication of cytoplasmic DNA viruses and'large' bacteriophages -- Retroviruses: converting RNA to DNA -- Human immunodeficiency virus type 1 (HIV-1) and related lentiviruses -- Hepadnaviruses: variations on the retrovirus theme -- The molecular genetics of viruses -- Molecular pathogenesis -- Viral bioinformatics and beyond -- Viruses and the future: problems and promises ER -