TY - BOOK AU - Rapley,Ralph AU - Harbron,Stuart TI - Molecular analysis and genome discovery SN - 0471498475 (hc.) PY - 2004/// CY - Chichester, West Sussex, England PB - John Wiley & Sons KW - Pharmacogenetics KW - methods KW - Genetic Techniques KW - Pharmaceutical Preparations KW - metabolism KW - Drug Design KW - Biological Markers KW - Quantitative Structure-Activity Relationship KW - Molecular diagnosis KW - Genomics KW - Proteomics KW - Pharmacogenomics KW - Polymerase chain reaction N1 - Pharmacogenetics and pharmacogenomics: an overview / W. Kalow -- Quantitative TaqMan real-time PCR: diagnostic and scientific applications / Jörg Dötsch, Ellen Schoof, and Wolfgang Rascher -- Hybridization probes for real-time PCR / Elaine Lyon -- An overview of genotyping and single nucleotide polymorphisms (SNP) / Ivo Glynne Gut -- High-throughput mutation screening / Paal Skytt Andersen and Lars Allan Larsen -- Determination of nucleic acid sequence by pyrosequencing / Elaine Elahi and Mostafa Ronaghi -- An introduction to DNA chips / Magdalena Gabig-Ciminska and Andrzej Ciminski -- Overview of microarrays in genomic analysis / Janette K. Burgess -- Overview of differential gene expression by high-throughput analysis / Kin-Ying To --; Aptamers: powerful molecular tools for therapeutics and diagnostics / Eva Baldrich i Rubio, Mónica Campàs i Homs, and Ciara K. O'Sullivan -- Chip-based proteomics technology / Mikhail Soloviev, Richard Barry, and Jon Terrett -- Infectomics overview: holistic and integrative studies of infectious diseases / Sheng-He Huang and Ambrose Jong -- The drug discovery process / Roberto Solari -- Structure-based drug discovery / Chen-Chen Kan, Kevin Hambly, and Derek A. Debe -- Protein interaction-targeted drug discovery / Gary Hudes, Sanjay Menon, and Erica A. Golemis -- Overview of quantitative structure-activity relationships (QSAR) / David A. Winkler ER -