Pharmaceutical bioassays : methods and applications / Shiqi Peng, Ming Zhao.

Includes bibliographical references and index.

Methods and application of anticancer bioassays / Shiqi Peng -- Methods and applications of antiviral assays / Shiqi Peng, Ming Zhao, and Chunying Cui -- Methods and applications of antitubercular assays / Shiqi Peng, Ming Zhao, and Chunying Cui -- Methods and applications of thrombus-related assayss / Ming Zhao -- Methods and applications of anticoagulation assays / Ming Zhao -- Methods and applications of blood pressure-related assays / Ming Zhao -- Methods and applications assays related to Parkinson's Disease and Graves' Disease / Shiqi Peng -- Methods and applications of Alzheimer's disease assays / Shiqi Peng -- Methods and applications of antiosteoporosis assays / Ming Zhao -- Methods and applications of immunomodulating assays / Shiqi Peng -- Methods and application of anti-inflammatory assays / Ming Zhao -- Methods and application of antioxidant activity assays / Shiqi Peng -- Methods and applications of analgesic assays / Ming Zhao -- Methods and applications of epilepsy assays / Ming Zhao, Shiqi Peng, and Guohui Cui -- Methods and applications of diabetes assays / Ming Zhao, Shiqi Peng, and Guohui Cui -- Methods and applications of assays for toxins from microorganisms / Shiqi Peng -- Methods and applications of toxicity assays for chemicals / Shiqi Peng -- Methods and applications of hepatoxicity and hepatoprotective assays / Shiqi Peng -- Methods and applications of estrogen assays / Shiqi Peng -- Methods and applications of antimalarial assays / Shiqi Peng -- Methods and applications of cytogenetic receptor and enzyme assays / Shiqi Peng.

The definitive compendium of bioassay procedures and applications. A virtual encyclopedia of key bioassay protocols, this up-to-date, essential resource reviews the methods and applications of bioassays that quantify drug activity and evaluate the validity of pharmacological models. Demonstrating the specific ways in which various pharmaceutical bioassays interpret the activity of drug molecules, the book covers the evaluation and screening of drug compounds in a wide spectrum of therapeutic categories. Throughout, the authors use various models to link experimental observations with findings that clarify the effect of drug compounds on cellular biology and measure the pharmacological activity of chemical substances. This provides an important technological platform for successful drug research and clinical therapy, making Pharmaceutical Bioassays an ideal sourcebook for pharmacologists, pharmaceutical and medical researchers, analytical chemists, toxicologists, and students. Just as a fundamental knowledge of pharmaceutical bioassays is vital to understanding how bioactive agents and new drugs are defined, discovered, and developed, so too is this indispensable reference, which: Offers a complete reference on pharmaceutical bioassays and their specific applications in the assessment of therapies for cancer, Alzheimer's, diabetes, epilepsy, inflammation, antimalarials, pharmacogenomics, and other major therapeutic areas; Covers bioassays that measure toxicity, including those for chemical toxicity and hepatoxicity-a particularly significant consideration in the development of safe and tolerable medications; Highlights clinically relevant methods, ideas, and techniques to support any pharmaceutical researcher; Suggests guidelines and systems to enhance communication between pharmacologists, chemists, and biologists; Provides an informative analysis of pharmaceutical bioassay technologies and lab applications.

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