Opportunistic protozoa in humans / series editors, J.R. Baker, R. Muller and D. Rollinson ; guest editor, S. Tzipori.

Includes bibliographical references and index.

Front Cover; Opportunistic Protozoa in Humans; Copyright Page; Contents; Contributors to Volume 40; Preface; PART 1: CRYPTOSPORIDIUM PARVUM AND RELATED GENERA; Introduction to Crytosporidum parvum; Chapter 1. Natural History and Biology of Cryptosporidium parvum; 1. Introduction; 2. Natural History and Chronology; 3. Life Cycle as Related to Control; 4. Classification and Taxonomy; 5. Risk to Humans from Infected Animals; 6. The Unique Intracellular Niche of Cryptosporidium; 7. Concluding Remarks; References.

Chapter 2. Human Cryptosporidiosis: Epidemiology, Transmission, Clinical Disease, Treatment, and Diagnosis1. Introduction; 2. Epidemiology; 3. Transmission; 4. Clinical Disease; 5. Treatment; 6. Diagnosis; References; Chapter 3. Innate and Cell-mediated Immune Responses to Cryptosporidium parvum; 1. Introduction; 2. Innate Immunity; 3. Cryptosporidium parvum-specific Cell-mediated Immunity; 4. Immunotherapy; 5. Concluding Remarks; References; Chapter 4. Antibody-based Immunotherapy of Cryptosporidiosis; 1. Introduction: Rationale for Therapy using Antibodies to Combat Cryptosporidiosis.

2. Practical Considerations for Antibody Therapy3. Early Studies of Immunotherapy for Cryptosporidiosis; 4. Laboratory Investigations of Anti-Cryptosporidium Antibodies; 5. Studies in Humans using Antibodies; 6. Future Prospects; References; Chapter 5. Cryptosporidium: Molecular Basis of Host-Parasite Interaction; 1. Introduction; 2. Oocysts and the Molecular Basis of Excystation and Oocyst Wall Formation; 3. Invasive (Zoite) Stages and the Molecular Basis of Attachment, Invasion, and Parasitophorus Vacuole Formation.

4. Intracellular Stages and the Molecular Basis of Stage Differentiation and Parasite Metabolism5. Future Perspectives; 6. Concluding Remarks; References; Chapter 6. Cryptosporidiosis: Laboratory Investigations and Chemotherapy; 1. Introduction; 2. Production of Oocysts for Biomedical Research; 3. Propagation in Cell Culture; 4. Animal Models; 5. New Approaches to Drug Design; 6. Laboratory Investigations on Drugs Presently Used in Humans; 7. Concluding Remarks; References; Chapter 7. Genetic Heterogeneity and PCR Detection of Cryptosporidium parvum.

1. Relevance of Studying Polymorphism in C. parvum2. Heterogeneity in Cryptosporidium; PCR Detection of C. parvum; References; Chapter 8. Water-borne Cryptosporidiosis: Detection Methods and Treatment Options; 1. Water-borne Outbreaks: A Brief History; 2. Occurrence of Cryptosporidium in Source Water; 3. Detection of Cryptosporidium in Water; 4. Regulatory Status and Environmental Laws; 5. Water Treatment Options; References; PART 2: ENTEROCYTOZOON BIENEUSI AND OTHER MICROSPORIDIA; Introduction to Microsporidia; Chapter 9. Biology of Microsporidian Species Infecting Mammals; 1. Introduction.

Due to the advent of AIDS, there is currently great interest in opportunistic infections in people with compromised immune systems. This special volume of Advances in Parasitology<$> provides a detailed account ofthe pathogens associated with human enteric diseases, Cryptosporidium parvum, Enterocytozoon bieneusi<$> and Cyclospora cayetanensis<$>. This volume is essential for all parasitologists working on opportunistic protozoa.

Print version record.

Elsevier ScienceDirect All Books