Advances in statistical methods for the health sciences : applications to cancer and aids studies, genome sequence analysis, and survival analysis / Jean-Louis Auget, N. Balakrishnan, Mounir Mesbah, Geert Molenberghs. Jean-Louis Auget... [et al.], editors

International conference proceedings

Includes bibliographical references and index

Systematic review of multiple studies of prognosis: the feasibility of obtaining individual patient data -- On statistical approaches for the multivariable analysis of prognostic marker studies -- Where next for evidence synthesis of prognostic marker studies? Improving the quality and reporting of primary studies to facilitate cinically relevant evidence-based results -- Sentinel event methods for monitoring unanticipated adverse events -- Spontaneous reporting system modelling for the evaluation of automatic signal generation methods in pharmacovigilance -- Latent covariates in generalized linear models: a Rasch model approach -- Sequential analysis of quality of life measurements with the mixed partial credit model -- A Parametric degradation model used in reliability, survival analysis, and quality of life -- Agreement between two ratings with different ordinal scales -- The role of correlated frailty models in studies of human health, ageing, and longevity -- Prognostic factors and prediction of residual survival for hospitalized elderly patients -- New models and methods for survival analysis of experimental data -- Uniform consistency for conditional lifetime distribution estimators under random right-censorship -- Sequential estimation for the semiparametric additive hazard model -- Variance-estimation of a survival function with doubly censored failure time data -- Statistical models and artificial neural networks: supervised classification and prediction via soft trees -- Multilevel clustering for large databases -- Neural networks: an application for predicting smear negative pulmonary tuberculosis -- Assessing drug resistance in HIV infection using viral load using segmented regression -- Assessment of treatment effects on HIV pathogenesis under treatment by state space models -- Safety assessment versus efficacy assessment --

Cancer clinical trials with efficacy and toxicity endpoints: a simulation study to compare two nonparametric methods -- Safety assessment in pilot studies when zero events are observed -- An assessment of up-and-down designs and associated estimators in phase I trials -- Design of multiventre clinical trials with random enrolment -- Statistical methods for combining clinical trials phases II and III - SCPRT: a sequential procedure that gives another reason to stop clinical trials early -- Seasonality assessment for biosurveillance systems -- Comparison of three convolution prior spatial models for cancer incidence -- Longitudinal analysis of short-term bronchiolitis air pollution assication using semiparametric models -- Are there correlated genomic substitutions? -- Swiss federal veterinary office risk assessments: advantages and limitations of the qualitative method -- Qualitative risk analysis in animal health: a methodological example