Molecular and genetic analysis of human traits / (Record no. 690210)
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| fixed length control field | 08276cam a2200769Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250919212026.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cn||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 171212s2001 mauaf ob 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780470760079 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0470760079 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780470759806 |
| Qualifying information | (electronic bk. ; |
| -- | Adobe Reader) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0470759801 |
| Qualifying information | (electronic bk. ; |
| -- | Adobe Reader) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 1281321613 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9781281321619 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780632043699 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 0632043695 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1002/9780470760079 |
| Source of number or code | doi |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | DEBSZ |
| System control number | 39617874X |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | DEBSZ |
| System control number | 452483697 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | DEBBG |
| System control number | BV043387441 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)212130183 |
| Canceled/invalid control number | (OCoLC)230187845 |
| -- | (OCoLC)244449697 |
| -- | (OCoLC)298254454 |
| -- | (OCoLC)505138213 |
| -- | (OCoLC)646751229 |
| -- | (OCoLC)746573257 |
| -- | (OCoLC)815566378 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)ocn212130183 |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | 10.1002/9780470760079 |
| Source of stock number/acquisition | Wiley InterScience |
| Note | http://www3.interscience.wiley.com |
| 037 ## - SOURCE OF ACQUISITION | |
| Stock number | B24FD63D-6690-4386-B285-81FA32787345 |
| Source of stock number/acquisition | OverDrive, Inc. |
| Note | http://www.overdrive.com |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] | |
| Level of rules in bibliographic description | 201902131500 |
| Level of effort used to assign nonsubject heading access points | murni |
| Level of effort used to assign subject headings | 201712120913 |
| Level of effort used to assign classification | hafiz |
| y | 12-08-2017 |
| z | hafiz |
| w | MYUKM (1).mrc |
| x | 53 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | DG1 |
| Language of cataloging | eng |
| Description conventions | pn |
| Transcribing agency | DG1 |
| Modifying agency | YDXCP |
| -- | DG1 |
| -- | IDEBK |
| -- | OCLCQ |
| -- | OCLCF |
| -- | OCLCO |
| -- | OCLCA |
| -- | NLGGC |
| -- | TEFOD |
| -- | BTCTA |
| -- | NST |
| -- | UBY |
| -- | E7B |
| -- | REDDC |
| -- | EBLCP |
| -- | DEBSZ |
| -- | OCLCQ |
| -- | TEFOD |
| -- | COO |
| -- | OCLCQ |
| -- | DEBBG |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | QH431 |
| Item number | .M3226 2001eb |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | 2000 N-573 |
| 060 #4 - NATIONAL LIBRARY OF MEDICINE CALL NUMBER | |
| Classification number | QZ 50 |
| Item number | M354m 2001 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MFN |
| Source | bicssc |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | SOC |
| Subject category code subdivision | 002020 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 599.93/5 |
| Edition information | 22 |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Maroni, Gustavo. |
| 245 10 - TITLE STATEMENT | |
| Title | Molecular and genetic analysis of human traits / |
| Statement of responsibility, etc. | Gustavo Maroni. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Place of publication, distribution, etc. | Malden, MA : |
| Name of publisher, distributor, etc. | Blackwell Science, |
| Date of publication, distribution, etc. | ©2001. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xii, 274 pages, [4] pages of color plates) : |
| Other physical details | illustrations |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Cover -- Contents -- PREFACE -- CHAPTER 1 The Inheritance of Simple Mendelian Traits in Humans -- DETECTING MENDELIAN INHERITANCE IN HUMANS -- Test-Crosses and Pure Lines versus Pedigrees and Inferred Genotypes -- PATTERNS OF INHERITANCE AND EXAMPLES -- Autosomal Dominant Traits -- Autosomal Recessive Traits -- X-Linked Recessive Traits -- THE USE OF PEDIGREES TO PREDICT THE RESULTS OF MATINGS -- Probability of Individual Genotypes -- Probability of Group Outcomes -- GATHERING DATA TO TEST THE MODE OF INHERITANCE OF A TRAIT -- Pooling Data from Many Families and Ascertainment Errors -- INHERITANCE OF MULTIPLE TRAITS: INDEPENDENT ASSORTMENT AND LINKAGE -- Determination of Linkage from Human Pedigrees -- Genetic Recombination and LOD Scores -- Informative and Noninformative Matings -- Neutral Polymorphisms, Marker Loci, and Genetic Maps -- CONCLUSION -- EXERCISES -- REFERENCES -- Box 1.1 Early observations of Mendelian inheritance in humans -- Box 1.2 Internet sites -- EXAMPLE 1.1 Linkage of the Huntington's disease gene to an RFLP -- CHAPTER 2 Hereditary Traits That Do Not Show a Simple Mendelian Pattern -- SINGLE-GENE TRAITS LACKING A SIMPLE MENDEUAN PATTERN -- Variable Exprrssiviy and Incomplete Penetrance -- Complementation -- Phenocopies and Pleiotropy -- QUANTITATIVE TRAITS -- Multiple Alleles -- Polygenic Inheritance -- Major and Minor Genes -- COMPLEX TRAITS -- Epidemiological Analysis of Complex Traits -- LOCALIZATION OF GENES RESPONSIBLE FOR COMPLEX AND QUANTITATIVE TRAITS -- Linkage Analysis of Complex Traits -- Affected Pedigree Member (APM) or Allele-Sharing Methods -- Allelic Association -- Candidate Gene -- CONCLUSION: NATURE VERSUS NURTURE -- EXERCISES -- REFERENCES -- Example 2.1. Familial psoriasis -- Example 2.2. Familial breast cancer -- Example 2.3. Insulin-dependent diabetes mellitus -- Example 2.4. Male homosexuality -- Example 2.5. Dyslexia -- Example 2.6. Nonsyndromal autosomal recessive deafness -- Example 2.7. Neuroticism and genes for serotonin metabolism -- CHAPTER 3 Genome Organization I -- UNEXPRESSED DNA, REPETITIVE AND UNIQUE SEQUENCES -- Clustered, Highly Repetitive Sequences -- Small-Cluster, Intermediately Repeated DNA -- Dispersed, Intermediately Repeated Sequences -- Unique Sequence DNA -- EXPRESSED DNA, GENES AND GENE FAMILIES -- The Organization of RNA Polymerase I1 Genes: Intmns and Exons -- Gene Families -- Ribosomal RNA Genes -- CONCLUSION -- EXERCISES -- REFERENCES -- Box 3.1. Internet sites -- Example 3.1. The a family of highly repetitive DNA -- Example 3.2. Collagen -- Example 3.3. Cystic fibrosis -- Example 3.4. Duchenne muscular dystmphy -- Example 3.5. The globin gene family -- Example 3.6. The retinal visual pigments -- CHAPTER 4 Genome Organization II -- ISOLATION AND CHARACTERIZATION OF HUMAN GENES -- Expression Cloning -- Cloning by Homology to Other Species -- Reverse Genetics -- Positional Cloning -- THE HUMAN GENOME PROJECT -- The Genetic Map -- Physical Maps -- Other Tools -- The Sequence-Tagged Site (STS) Proposal -- Advances in the Human Genome Project -- CONCLUSION: THE END IN SIGHT -- EXERCISES -- REFERENCES -- Box 4.1. Ethical concerns -- Box 4.2. You're going to patent my genes71 -- Box 4.3. Internet sites -- Example 4.1. Isolation. |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | 'Molecular and Genetic Analysis of Human Traits' is the first concise presentation of what is unique about human genetics. Designed to introduce human genetics to undergraduate and graduate students who are familiar with basic genetics, the text assumes knowledge of meiosis and Mendelian genetics as well as the basic principles of transmission of information from DNA to RNA to proteins. Professor Maroni's engaging presentation is both authoritative and student-oriented. Outstanding features highlight this groundbreaking first edition: Incorporates two basic themes throughout:'How do we establish that a trait is hereditary?' and'How can the properties of a trait be explained by the underlying molecular causes?' ; compares standard genetic approaches to those needed for studying inheritance in humans; prepares students for understanding the original literature by clear presentation of actual experiments; chapters 3 and 4 include thorough treatment of the human genome project as explained in its rationale, its development, and its conclusion; and, provides a comprehensive explanation of how genes are mapped by describing the four methods most commonly used: linkage analysis, affected pedigree member, allelic association, and candidate gene. It offers exceptional student-friendly pedagogy: Describes a wealth of applications, including: how genetics is used in understanding cancer (Chapter 8) and how genetic predictions impact counseling for families who are at risk (Chapter 9); addresses relevant clinical examples and key related ethical issues; the Human Genome Project Box includes the latest, culminating research; Internet Site Boxes refer to pertinent human genetics; and, URLs, chapter opening contents, margin notes, two-color figures, four-color insert, examples, conclusions, end-of-chapter exercises, over 150 original literature citation, and much more. |
| 588 0# - SOURCE OF DESCRIPTION NOTE | |
| Source of description note | Print version record. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Human genetics. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medical genetics. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetics, Medical. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Predisposition to Disease. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genome, Human. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Genetic Linkage. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SOCIAL SCIENCE |
| General subdivision | Anthropology |
| -- | Physical. |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Human genetics. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst00963075 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medical genetics. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst01014133 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic resource. |
| 710 2# - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Wiley InterScience (Online service) |
| 773 0# - HOST ITEM ENTRY | |
| Title | Wiley e-books |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Maroni, Gustavo. |
| Title | Molecular and genetic analysis of human traits. |
| Place, publisher, and date of publication | Malden, MA : Blackwell Science, ©2001 |
| International Standard Book Number | 0632043695 |
| -- | 9780632043699 |
| Record control number | (DLC) 00023792 |
| -- | (OCoLC)43520935 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://onlinelibrary.wiley.com/book/10.1002/9780470760079">https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://onlinelibrary.wiley.com/book/10.1002/9780470760079</a> |
| Public note | Wiley Online Library |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b16537439 |
| b | 2022-11-02 |
| c | 2019-11-12 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Suppress in OPAC | No |
| 914 ## - VTLS Number | |
| VTLS Number | vtls003628665 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Library | |
| Operator's initials, OID (RLIN) | 2017-08-12 |
| Cataloger's initials, CIN (RLIN) | m |
| Material Type (Sierra) | E-Book |
| Language | English |
| Country | |
| -- | 0 |
| -- | .b16537439 |
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