Epigenetic cancer therapy / (Record no. 613494)
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| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250919085811.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m o d u |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr ||||||||||| |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 161221s2015 ne o 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780128002247 |
| Qualifying information | electronic bk. |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 0128002247 |
| Qualifying information | electronic bk. |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780128002063 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 0128002069 |
| 029 0# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | NLGGC |
| System control number | 394179072 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | CHVBK |
| System control number | 33870972X |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | CHBIS |
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| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | CHVBK |
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| OCLC library identifier | CHDSB |
| System control number | 006420722 |
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| OCLC library identifier | CHVBK |
| System control number | 341786853 |
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| OCLC library identifier | CHBIS |
| System control number | 010548004 |
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| OCLC library identifier | DEBSZ |
| System control number | 451527356 |
| 029 1# - OTHER SYSTEM CONTROL NUMBER (OCLC) | |
| OCLC library identifier | GBVCP |
| System control number | 832501999 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)913208366 |
| Canceled/invalid control number | (OCoLC)913695384 |
| 035 ## - SYSTEM CONTROL NUMBER | |
| System control number | (OCoLC)ocn913208366 |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] | |
| y | 12-21-2016 |
| z | hafiz |
| w | metacoll.MYUKM.updates.D20160920.T210208.sdallbooks.1 (perolehan)hafizupload21122016.mrc |
| x | 190 |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLGGC |
| Language of cataloging | eng |
| Description conventions | rda |
| -- | pn |
| Transcribing agency | NLGGC |
| Modifying agency | NST |
| -- | OPELS |
| -- | NST |
| -- | YDXCP |
| -- | EBLCP |
| -- | COO |
| -- | IDEBK |
| -- | CDX |
| -- | DEBSZ |
| -- | OCLCF |
| 049 ## - LOCAL HOLDINGS (OCLC) | |
| Holding library | MAIN |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER | |
| Classification number | RC271.G45 |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 014000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 022000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 112000 |
| Source | bisacsh |
| 072 #7 - SUBJECT CATEGORY CODE | |
| Subject category code | MED |
| Subject category code subdivision | 045000 |
| Source | bisacsh |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.99/40695 |
| Edition information | 23 |
| 245 00 - TITLE STATEMENT | |
| Title | Epigenetic cancer therapy / |
| Statement of responsibility, etc. | edited by Steven G. Gray. |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Place of production, publication, distribution, manufacture | Amsterdam : |
| Name of producer, publisher, distributor, manufacturer | Elsevier : |
| -- | Academic Press, |
| Date of production, publication, distribution, manufacture, or copyright notice | [2015] |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | ò015 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 online resource (xxvi, 721 pages) |
| 336 ## - CONTENT TYPE | |
| Content type term | text |
| Content type code | txt |
| Source | rdacontent |
| 337 ## - MEDIA TYPE | |
| Media type term | computer |
| Media type code | c |
| Source | rdamedia |
| 338 ## - CARRIER TYPE | |
| Carrier type term | online resource |
| Carrier type code | cr |
| Source | rdacarrier |
| 490 0# - SERIES STATEMENT | |
| Series statement | Translational Epigenetics Series |
| 500 ## - GENERAL NOTE | |
| General note | Includes index. |
| 500 ## - GENERAL NOTE | |
| General note | Academic Press is an imprint of Elsevier. |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Includes bibliographical references at the end of each chapters and index. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Front Cover; Epigenetic Cancer Therapy; Copyright Page; Contents; List of Contributors; 1 Introduction; 1 Introduction to the Area (Key Concepts); 2 Epigenetics and Cancer; 3 Targeting Aberrant Epigenetics; 4 Issues to Overcome/Areas of Concern; 5 Future Directions: Translation to the Clinic; References; 1 Introduction and Key Concepts; 2 DNA Methylation and Hydroxymethylation in Cancer; 1 Introduction; 2 Epigenetics; 2.1 Chromatin Structure; 2.2 DNA Methylation in Cellular Homeostasis; 2.2.1 Genomic distribution of DNA methylation; 2.2.2 Functional role of DNA methylation |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2.2.3 DNA methyltransferases2.2.4 Recruitment of DNMTs; 2.3 DNA Demethylation; 3 DNA Methylation Patterns in Cancer; 3.1 Hypermethylation in Cancer; 3.2 Hypomethylation in Cancer; 3.3 Methods for 5mC Detection; 4 Aberrations of Enzymes Involved in DNA Methylation Homeostasis in Cancer; 4.1 DNA Methyltransferase; 4.2 TET Proteins; 4.3 Isocitrate Dehydrogenases; 4.4 Succinate Dehydrogenases; 5 DNA Hydroxymethylation in Cancer; 5.1 Methods for 5hmC Detection; 5.1.1 Affinity-based enrichment approach; 5.1.2 Chemical methods; 5.1.3 Quantitative methods at single base resolution |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 5.1.4 Third-generation sequencing5.2 DNA Hydroxymethylation Patterns in Cancer; 6 Conclusion; References; 3 Writers, Readers, and Erasers of Epigenetic Marks; 1 Introduction; 2 Writers; 2.1 DNA Methyltransferases; 2.2 Histone Lysine Methyltransferases; 2.3 Protein Arginine Methyltransferases; 2.4 Histone Acetyltransferases; 3 Readers; 3.1 Methyl-CpG-Binding Proteins; 3.2 Histone Methylation-Binding Domains; 3.3 Histone Acetylation-Binding Domains; 4 Erasers; 4.1 Proteins Involved in DNA Demethylation; 4.2 Histone Demethylases; 4.3 Histone Deacetylases (HDACs) |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 5 Interactions between the Various Components6 Epigenetics and Cancer; 6.1 DNA Methylation and Cancer; 6.2 Histone Methylation and Cancer; 6.3 Histone Acetylation and Cancer; 7 Epigenetic Proteins as Therapeutic Targets; 8 Conclusion and Future Opportunities; References; 4 MicroRNAs and Cancer; 1 miRNA Biogenesis and Functionality; 2 miRNAs in Cancer Biology; 3 miRNA: An Epigenetic Perspective; 3.1 Epigenetic Alteration of miRNA Expression; 3.2 Epi-miRNA; 3.3 miRNA with Epigenetic Functions; 4 miRNA Epigenetic Therapy; 4.1 miRNA Inhibition in Cancer; 4.2 miRNA Replacement in Cancer |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4.3 Small-Molecule-Based miRNA Modulation5 Future Perspectives; Acknowledgments; References; 5 Long Noncoding RNAs and Cancer; 1 Introduction; 2 Classification and Nomenclature of lncRNAs; 2.1 Classification; 2.2 Nomenclature; 3 Mechanisms of lncRNA Function; 3.1 lncRNAs as Decoys and Guides; 3.2 lncRNAs as Scaffolds; 3.3 lncRNAs as Signaling Molecules; 3.4 miRNA Sequestration; 3.5 lncRNAs and Epigenetic Regulation; 3.5.1 H19; 3.5.2 AIR and KCNQ1OT1; 3.5.3 lincRNAs; 4 lncRNAs and Human Disease; 4.1 Prognostic Markers; 4.1.1 lncRNAs in the circulation |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector. The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver). The bo. |
| 590 ## - LOCAL NOTE (RLIN) | |
| Local note | Elsevier |
| Provenance (VM) [OBSOLETE] | ScienceDirect All Books |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cancer |
| General subdivision | Gene therapy. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Epigenetics. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MEDICAL / Clinical Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MEDICAL / Diseases |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MEDICAL / Evidence-Based Medicine |
| Source of heading or term | bisacsh |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | MEDICAL / Internal Medicine |
| Source of heading or term | bisacsh |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cancer -- Treatment. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cancer. |
| 650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Medicine. |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cancer |
| General subdivision | Gene therapy. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst00845367 |
| 650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Epigenetics. |
| Source of heading or term | fast |
| Authority record control number or standard number | (OCoLC)fst01893642 |
| 655 #4 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 655 #0 - INDEX TERM--GENRE/FORM | |
| Genre/form data or focus term | Electronic books. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Gray, Steven G., |
| Relator term | editor. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY | |
| Relationship information | Print version: |
| Main entry heading | Gray, Steven |
| Title | Epigenetic Cancer Therapy |
| Place, publisher, and date of publication | Burlington : Elsevier Science,c2015 |
| International Standard Book Number | 9780128002063 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780128002063">https://eresourcesptsl.ukm.remotexs.co/user/login?url=http://www.sciencedirect.com/science/book/9780128002063</a> |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) | |
| a | .b16401086 |
| b | 2022-11-02 |
| c | 2019-11-12 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Suppress in OPAC | No |
| 914 ## - VTLS Number | |
| VTLS Number | vtls003614213 |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) | |
| Library | |
| Operator's initials, OID (RLIN) | 2016-08-12 |
| Cataloger's initials, CIN (RLIN) | m |
| Material Type (Sierra) | E-Book |
| Language | English |
| Country | |
| -- | 0 |
| -- | .b16401086 |
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