MARC details
| 000 -LEADER |
|---|
| fixed length control field |
04131cam a2200433 a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20250918145702.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
111202s2010 enka b 001 0 eng |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
9780521887236 (hardback) |
| Terms of availability |
RM428.27 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| International Standard Book Number |
0521887232 (hardback) |
| 039 #9 - LEVEL OF BIBLIOGRAPHIC CONTROL AND CODING DETAIL [OBSOLETE] |
|---|
| Level of rules in bibliographic description |
201505081158 |
| Level of effort used to assign nonsubject heading access points |
sue |
| Level of effort used to assign subject headings |
201505081156 |
| Level of effort used to assign classification |
sue |
| Level of effort used to assign subject headings |
201503311149 |
| Level of effort used to assign classification |
wafi |
| Level of effort used to assign subject headings |
201201030959 |
| Level of effort used to assign classification |
ruzini |
| y |
12-02-2011 |
| z |
razalis |
| 040 ## - CATALOGING SOURCE |
|---|
| Original cataloging agency |
UKM |
| Description conventions |
rda |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QV744.D794 2010 9 |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QV744 |
| Local cutter number (OCLC) ; Book number/undivided call number, CALL (RLIN) |
.D794 2010 9HUKMPRA |
| 090 ## - LOCALLY ASSIGNED LC-TYPE CALL NUMBER (OCLC); LOCAL CALL NUMBER (RLIN) |
|---|
| Classification number (OCLC) (R) ; Classification number, CALL (RLIN) (NR) |
QV744 |
| Local cutter number (OCLC) ; Book number/undivided call number, CALL (RLIN) |
.D794 2010 9 |
| 245 00 - TITLE STATEMENT |
|---|
| Title |
Drug design : |
| Remainder of title |
structure- and ligand-based approaches / |
| Statement of responsibility, etc. |
edited by Kenneth M. Merz, Dagmar Ringe, Charles H. Reynolds |
| 264 #1 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Place of production, publication, distribution, manufacture |
Cambridge [U.K.] ; |
| -- |
New York : |
| Name of producer, publisher, distributor, manufacturer |
Cambridge University Press, |
| Date of production, publication, distribution, manufacture, or copyright notice |
2010. |
| 264 #4 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE |
|---|
| Date of production, publication, distribution, manufacture, or copyright notice |
©2010. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Extent |
x, 274 pages : |
| Other physical details |
illustrations (some col.) ; |
| Dimensions |
29 cm. |
| 336 ## - CONTENT TYPE |
|---|
| Content type term |
text |
| Source |
rdacontent |
| 337 ## - MEDIA TYPE |
|---|
| Media type term |
unmediated |
| Source |
rdamedia |
| 338 ## - CARRIER TYPE |
|---|
| Carrier type term |
volume |
| Source |
rdacarrier |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
|---|
| Bibliography, etc. note |
Includes bibliographical references and index. |
| 505 8# - FORMATTED CONTENTS NOTE |
|---|
| Formatted contents note |
Machine generated contents note: 1. Computational chemistry in drug discovery William L. Jorgensen; Part I. Structural Biology: 2. X-Ray crystallography Gregory Petsko and Dagmar Ringe; 3. Fragment-based approaches to structural biology Stephen K. Burley, Gavin Hirst, Paul Sprengeler, and Siegfried Reich; 4. Application of NMR in drug discovery Christopher A. Lepre, Peter J. Connolly, and Jonathan M. Moore; Part II. Computational Chemistry Methodology: 5. Free energy calculations in structure-based drug design Michael R. Shirts, David L. Mobley, and Scott P. Brown; 6. Molecular dynamics in structure-based drug design Fangyu Ding and Carlos Simmerling; 7. Docking: a domesday report Martha S. Head; 8. Quantum mechanics in drug discovery Kenneth M. Merz; 9. Pharmacophore methods Steven L. Dixon; 10. QSAR in drug discovery Alexander Tropsha; 11. ADME-Tox William J. Egan; Part III. Applications to Drug Discovery: 12. Principles of computer-aided drug design Charles H. Reynolds; 13. Case study: p38 Arthur M. Doweyko; 14. HIV protease: de;j...-vu all over again M. Katharine Holloway, Nigel J. Liverton, John A. McCauley, Michael T. Rudd, John W. Butcher, Steve S. Carroll, Jillian DiMuzio, Christine Fandozzi, Kevin F. Gilbert, Shi-Shan Mao, Charles J. MacIntyre, Kevin T. Nguyen, Joseph J. Romano, Mark Stahlhut, Bang-Lin Wan, David B. Olsen, and Joseph P. Vacca; 15. Purine nucleoside phosphorylases as targets for transition-state analogue design Andrew S. Murkin and Vern L. Schramm; 16. GPCR 3D modeling Frank U. Axe; 17. Structure based design of potent glycogen phosphorylase inhibitors Qiaolin Deng |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc. |
'Structure-based (SBDD) and ligand-based (LBDD) drug design are extremely important and active areas of research in both the academic and commercial realms. This book provides a complete snapshot of the field of computer-aided drug design and associated experimental approaches. Topics covered include X-ray crystallography, NMR, fragment-based drug design, free energy methods, docking and scoring, linear-scaling quantum calculations, QSAR, pharmacophore methods, computational ADME-Tox, and drug discovery case studies. A variety of authors from academic and commercial institutions all over the world have contributed to this book, which is illustrated with more than 200 images. This is the only book to cover the subject of structure and ligand-based drug design, and it provides the most up-to-date information on a wide range of topics for the practicing computational chemist, medicinal chemist, or structural biologist'--Provided by publisher |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Drug Design. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Ligands. |
| 650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical term or geographic name entry element |
Structure-Activity Relationship. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Merz, Kenneth M., |
| Dates associated with a name |
1959- |
| Relator term |
author. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Ringe, Dagmar |
| Relator term |
author. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Reynolds, Charles H., |
| Dates associated with a name |
1957- |
| Relator term |
author. |
| 907 ## - LOCAL DATA ELEMENT G, LDG (RLIN) |
|---|
| a |
.b15205162 |
| b |
2021-05-28 |
| c |
2019-11-12 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
AM |
| Suppress in OPAC |
No |
| Call number prefix |
QV744.D794 2010 9 |
| 914 ## - VTLS Number |
|---|
| VTLS Number |
vtls003483871 |
| 990 ## - EQUIVALENCES OR CROSS-REFERENCES [LOCAL, CANADA] |
|---|
| Link information for 9XX fields |
mwafi/sue |
| 991 ## - LOCAL NOTE (NAMA FAKULTI/INSTITUT/PUSAT) |
|---|
| a |
Fakulti Farmasi, KKL |
| 991 ## - LOCAL NOTE (NAMA FAKULTI/INSTITUT/PUSAT) |
|---|
| a |
Jabatan Biokimia, Pra Klinikal PPUKM |
| 998 ## - LOCAL CONTROL INFORMATION (RLIN) |
|---|
| Library |
PERPUSTAKAAN DR ABDUL LATIFF |
| -- |
PERPUSTAKAAN PRAKLINIKAL |
| Operator's initials, OID (RLIN) |
2011-02-12 |
| Cataloger's initials, CIN (RLIN) |
m |
| Material Type (Sierra) |
Printed Books |
| Language |
English |
| Country |
|
| -- |
0 |
| -- |
.b15205162 |
