Systems metabolic engineering : methods and protocols /
Systems metabolic engineering : methods and protocols /
edited by Hal S. Alper.
- New York : Humana Press, 2013.
- xii, 474 p. : ill. ; cm.
- Methods in molecular biology ; v. 985 .
- Methods in molecular biology .
Includes bibliographical references and index.
Genome-scale model management and comparison / Automated genome annotation and metabolic model reconstruction in the SEED and model SEED / Metabolic model refinement using phenotypic microarray data / Linking genome-scale metabolic modeling and genome annotation / Resolving cell composition through simple measurements, genome-scale modeling, and a genetic algorithm / Guide to integrating transcriptional regulatory and metabolic networks using PROM (probabilistic regulation of metabolism) / Kinetic modeling of metabolic pathways : application to serine biosynthesis / Computational tools for guided discovery and engineering of metabolic pathways / Retrosynthetic design of heterologous pathways / Customized optimization of metabolic pathways by combinatorial transcriptional engineering / Adaptive laboratory evolution for strain engineering / Trackable multiplex recombineering for gene-trait mapping in E. coli / Identification of mutations in evolved bacterial genomes / Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies / 13C-based metabolic flux analysis : fundamentals and practice / Nuclear magnetic resonance methods for metabolic fluxomics / Using multiple tracers for 13C metabolic flux analysis / Isotopically nonstationary 13C metabolic flux analysis / Sample preparation and biostatistics for integrated genomics approaches / Targeted metabolic engineering guided by computational analysis of single-nucleotide polymorphisms (SNPs) / Linking RNA measurements and proteomics with genome-scale models / Comparative transcriptome analysis for metabolic engineering / Merging multiple omics datasets in silico : statistical analyses and data interpretation / Stephan Pabinger and Zlatko Trajanoski -- Scott Devoid ... [et al.] -- Pratish Gawand ... [et al.] -- Edik M. Blais, Arvind K. Chavali, and Jason A. Papin -- Ryan S. Senger and Hadi Nazem-Bokaee -- Evangelos Simeonidis, Sriram Chandrasekaran, and Nathan D. Price -- Kieran Smallbone and Natalie J. Stanford -- Matthew Moura, Linda Broadbelt, and Keith Tyo -- Pablo Carbonell, Anne-Gaelle Planson, and Jean-Loup Faulon -- Yongbo Yuan, Jing Du, and Huimin Zhao -- James Winkler, Luis H. Reyes, and Katy C. Kao -- Thomas J. Mansell, Joseph R. Warner, and Ryan T. Gill -- Liam Royce ... [et al.] -- Grant Gelderman and Lydia M. Contreras -- Tae Hoon Yang -- Shilpa Nargund ... [et al.] -- Maciek R. Antoniewicz -- Lara J. Jazmin and Jamey D. Young -- Hein Stam ... [et al.] -- D.B.R.K. Gupta Udatha ... [et al.] -- Christopher M. Gowen and Stephen S. Fong -- Shuobo Shi, Tao Chen, and Xueming Zhao -- Kazuharu Arakawa and Masaru Tomita.
9781627032988 (hbk.) RM452.28 1627032983
Metabolism.
Biomedical engineering.
Systems Biology.
Includes bibliographical references and index.
Genome-scale model management and comparison / Automated genome annotation and metabolic model reconstruction in the SEED and model SEED / Metabolic model refinement using phenotypic microarray data / Linking genome-scale metabolic modeling and genome annotation / Resolving cell composition through simple measurements, genome-scale modeling, and a genetic algorithm / Guide to integrating transcriptional regulatory and metabolic networks using PROM (probabilistic regulation of metabolism) / Kinetic modeling of metabolic pathways : application to serine biosynthesis / Computational tools for guided discovery and engineering of metabolic pathways / Retrosynthetic design of heterologous pathways / Customized optimization of metabolic pathways by combinatorial transcriptional engineering / Adaptive laboratory evolution for strain engineering / Trackable multiplex recombineering for gene-trait mapping in E. coli / Identification of mutations in evolved bacterial genomes / Discovery of posttranscriptional regulatory RNAs using next generation sequencing technologies / 13C-based metabolic flux analysis : fundamentals and practice / Nuclear magnetic resonance methods for metabolic fluxomics / Using multiple tracers for 13C metabolic flux analysis / Isotopically nonstationary 13C metabolic flux analysis / Sample preparation and biostatistics for integrated genomics approaches / Targeted metabolic engineering guided by computational analysis of single-nucleotide polymorphisms (SNPs) / Linking RNA measurements and proteomics with genome-scale models / Comparative transcriptome analysis for metabolic engineering / Merging multiple omics datasets in silico : statistical analyses and data interpretation / Stephan Pabinger and Zlatko Trajanoski -- Scott Devoid ... [et al.] -- Pratish Gawand ... [et al.] -- Edik M. Blais, Arvind K. Chavali, and Jason A. Papin -- Ryan S. Senger and Hadi Nazem-Bokaee -- Evangelos Simeonidis, Sriram Chandrasekaran, and Nathan D. Price -- Kieran Smallbone and Natalie J. Stanford -- Matthew Moura, Linda Broadbelt, and Keith Tyo -- Pablo Carbonell, Anne-Gaelle Planson, and Jean-Loup Faulon -- Yongbo Yuan, Jing Du, and Huimin Zhao -- James Winkler, Luis H. Reyes, and Katy C. Kao -- Thomas J. Mansell, Joseph R. Warner, and Ryan T. Gill -- Liam Royce ... [et al.] -- Grant Gelderman and Lydia M. Contreras -- Tae Hoon Yang -- Shilpa Nargund ... [et al.] -- Maciek R. Antoniewicz -- Lara J. Jazmin and Jamey D. Young -- Hein Stam ... [et al.] -- D.B.R.K. Gupta Udatha ... [et al.] -- Christopher M. Gowen and Stephen S. Fong -- Shuobo Shi, Tao Chen, and Xueming Zhao -- Kazuharu Arakawa and Masaru Tomita.
9781627032988 (hbk.) RM452.28 1627032983
Metabolism.
Biomedical engineering.
Systems Biology.